[Fundus changes in hyperlipidemia].

Of a total of 26 patients with hyperlipidemia, 4 developed flat yellow patches of varying size and shape in the macular area. In a different study a total of 9 subjects with similar flat yellow patches were examined; 6 had increased levels of serum cholesterol and triglycerides. The likelihood that such patients have hyperlipidemia is well over 50%.

[Correlation between bleb-like, fingerprint and map-like dystrophy of the cornea].

In epithelial basal membrane dystrophy of the cornea Bron's dystrophy plays a prominent role (frequently combined with fingerprint dystrophy). It can be visualized only in retroillumination, and is without doubt the most common corneal dystrophy. It should be distinguished from Cogan's microcysts, which were seen in only 11% of the authors patients.

[Electron-microscopic and biochemical characteristics of pterygia (author's transl)].

Histologically, pterygium is characterized, apart from the presence of typical collagen fibers, by the appearance of fibres which take up elastic stain but differ from normal elastic tissue, as was confirmed by electron-microscopic investigations. Thus, "elastoid degeneration" of collagen is characterized by the loss of the characteristic periodic fibril structure and by the appearance of coiled and knotty fibres. Collagen types in pterygium were identified biochemically for the first time.

[Serum immunofluorescence examination in loa ophthalmia (author's transl)].

Loaiasis is a chronic parasitic disease caused by the filaria Loa loa.As soon as the worm reaches the subconjunctival space local irration ensues. This so-called Loa ophthalmia necessitates immediate surgical intervention which can be performed under topical anesthesia, using the slit lamp.

[Maplike dystrophy of the cornea (author's transl)].

A report on 11 cases of maplike dystrophy of the cornea; it is characterized by the presence of fine whitish intraepithelial lines, which may easily be overlooked during biomicroscopic examination: they are most easily descernable in bright oblique illumination. Similarities with Cogan's, fingerprint, and bleblike dystrophy (Bron) are discussed, and the potential weakness of the corneal epithelium found in these patients is pointed out.

Erosive-ulcerative herpes simplex blepharitis.

In 28 subjects the diagnosis of an erosive-ulcerative herpes simplex blepharitis was confirmed by laboratory tests. The clinical manifestations were characterized by the presence of erosions of the intermarginal portion of the lid or the presence of skin ulcers located at the lid margin or the combination of both features, and usually by an absence of vesicular eruptions. Erosions of the intermarginal portion of the lid can readily be made visible by staining with fluorescein.

[Branch occlusion of the central retinal artery during coronary angiography (author's transl)].

A 49-year-old man went blind in his left eye during coronary angiography. The following day an occlusion of the inferior temporal and inferior nasal branch of the central retinal artery was detected, associated with a moderate papilledema of the inferior part of the optic disk as well as retinal edema of the inferior fundus. Fluorescein angiography confirmed the clinical diagnosis, perimetry revealed loss of visual field in the superior half.

[Risks associated with photocoagulation in proliferative diabetic retinopathy (author's transl)].

In 185 diabetics with proliferative diabetic retinopathy (d.r.) involving both eyes symmetrically we analyzed the indication for photocoagulation in borderline cases in which, despite complications (such as inducement of vitreoretinal retraction), the beneficial effect of photocoagulation outweighs the likelihoood of a spontaneous deleterious course.

[Bleb-like and fingerprint dystrophies of the cornea].

Within the past two years we have seen the "bleb-like dystrophy" of Bron and Brown in 30 patients. It is characterized by groups of subepithelial excrescences measuring 15-100 microms. These pathologic changes can only be discerned biomicroscopically by retro-illumination; they do not result in any opacification of the corneal epithelium or stroma.

[Fluorescence-angiography, infrared-photography and histology in malignant melanoma of the papilla (author's transl)].

In a 60-year-old female a juxtapapillary malignant melanoma of the choroid invading and strangling the prelaminary section of the optic nerve head, and being masked by a massive papilledema, could be revealed by combined application of ultrasonography, fluorescenceangiography and infrared-photography. The histological examination confirmed the clinical diagnosis.

[Treatment of herpes simplex of the lid margin with vidarabin ointment (author's transl)].

Twenty cases of herpes simplex of the lid margin were treated with vidarabin ointment applied topically 4 to 5 times daily together with an antibiotic ointment 2 to 4 times per day. Healing of the skin eruptions was observed within 3 to 12 days (average 6 days). Vidarabin eye ointment was well tolerated in all cases.

[Clinical experience in glaucoma surgery utilizing silicon catheters (author's transl)].

In 7 probands exhibiting haemorrhagic glaucoma a combined thermosclerostomy with insertion of a silicons tubing (with or without basal iridectomy) has been performed. The catheter had an inner diameter of 0,5 mm, measuring about 5 mm in length and projecting about 1,5 mm into the anterior chamber. The tubing has been anchored proximally with two nylon sutures (10--0) to the corneal wound edge going through full thickness cornea; the distal end has been anchored with two more nylon sutures to underlying sclera.

[Aqueous outflow following seton operations (author's transl)].

In 6 rabbits which had been submitted to a seton operation 2--6 months previously, the mode of aqueous outflow has been documented photographically after injection of fluorescein into the anterior chamber. In all 6 cases the catheter allowed direct passage of aqueous humour through its lumen into the subconjunctival space; further sources of diffuse aqueous egress were provable at the site of the corneo-slceral wound, either next to the catheter or aside from it. Additional drainage via preformed channels occurred through lymphatic vessels as well as through secondary aqueous veins.

[Experimental and clinical experiences with silicone catheters in fistulizing glaucoma surgery].

1. A historical revue of seton operations is presented, which were actually explored for the first time by Rollet in 1907. 2.

[Erosive-ulcerative type of herpes simplex of the lids (author's transl)].

In 14 patients the diagnosis of an erosive-ulcerative type of herpes simplex of the lids was made. It is characterized by erosions of the intermarginal portion of the lid or by erosions or ulcers of the skin, especially close to the lid margin. A combination of both clinical forms is possible.

[Glaucoma surgery with insertion of silicone catheters. A study based on animal experiments (author's transl)].

10 rabbits have been submitted to thermosklerostomy and insertion of a silicone catheter. The tube exhibiting an inner diameter of 0.5 mm and an outer diameter of 0.

[Growth hormone and diabetic retinopathy (author's transl)].

Changes in the serum level of growth hormone have been studied in 28 diabetics (6 exhibiting no diabetic retinopathy (d. r.), 10 displaying a non proliferative d.

[Treatment of herpes simplex keratitis with Vidarabin ointment (author's transl)].

In 20 cases of herpes simplex keratitis the efficacy of Vidarabin ointment has been tested, in 19 cases after corneal abrasion. The eyes were treated once a day and padded until the epithelial defects had closed. Thereafter the ointment was applied 4 times per day for about one week more.

[Retinal detachment following central vein occlusion. A comparative study by means of angiography and histology (author's transl)].

The comparison of the angiographic and histologic findings following central vein occlusion in a 42-year-old male suffering from arterial hypertension leads to the conclusion that a secondary arrhegmatic serous retinal detachment may be caused by a separation of the pigment epithelium with multiple defects in this layer.

Echography and histological studies in various eye conditions.

A correlation between A-scan echograms recorded clinically in vivo and histological studies of corresponding sections has been made in 42 eyes with intraocular pathological conditions. This study yielded both new and little known acoustic differential criteria for the diagnosis of retinoschisis, funnel-shaped vitreous detachments, serous as well as hemorrhagic retinal and choroidal detachments, intravitreal hemorrhages, and intraocular tumors.

[Herpes simplex of the lid margin (author's transl)].

Isolated herpes simplex affecting the lid margin can be distinguished from herpes simplex involving the entire eyelid by characteristic features. The typical intermarginal form of herpes-simplex-blepharitis presents itself as an erosion of about 3 mm in length which may be well discerned in detail after fluorescein staining. The skin adjecent to the lesion may also exhibit superficial ulceration, possibly being covered by crusts.