Measurement of glomerular filtration rate with chromium-51 ethylene diamino tetraacetic acid in the presence of gallium-67 citrate: a novel method for the solution of the problem.

Chromium-51 (⁵¹Cr)-ethylene diamino tetraacetic acid plasma clearance is commonly used in glomerular filtration rate measurements. In the presence of additional radionuclides in plasma samples, glomerular filtration rate may be seriously underestimated and a correction of the crosstalk interference may be necessary. This type of correction is problematic in the case of gallium-67 (⁶⁷Ga) mainly because of the close vicinity of its 300 keV photopeak with that of the 320 keV photopeak of ⁵¹Cr.