Publications by authors named "Efthimia Papacharalambous"
Article Synopsis
- Preeclampsia is a serious pregnancy-related condition characterized by high blood pressure, which can negatively impact fetal development.
- It can lead to short-term issues for the fetus and long-term complications for newborns due to impaired blood flow during critical developmental stages.
- The case presented involves a preterm baby who is small for their age, experiencing severe growth issues and gastrointestinal problems, born to a mother suffering from severe preeclampsia.
Objectives: Multiple pregnancies sustain the high pace of extreme prematurity. Little evidence is available about triplet gestation given the evolution in their management during the last decades The aim of the study was to compare the neonatal outcomes of triplets with those of matched singletons in a cohort study.
Methods: An observational retrospective cohort study of triplets and matched singletons born between 2004 and 2017 matched by gestational age was conducted.
Effectiveness and Safety of 4-factor Prothrombin Complex Concentrate (4PCC) in Neonates With Intractable Bleeding or Severe Coagulation Disturbances: A Retrospective Study of 37 Cases.
J Pediatr Hematol Oncol
April 2019
Background: To date, clinical experience with prothrombin complex concentrate (PCC) in the neonatal population has been limited.
Aim: The objective of this study was to describe our experience regarding the effectiveness and safety of PCC administration in newborns with severe bleeding or coagulopathy resistant to conventional therapy.
Methodology: We retrospectively analyzed data from 37 neonates with intractable bleeding or severe coagulation disturbances.
We describe the outbreak of a pan-susceptible Klebsiella pneumoniae strain in a neonatal intensive care unit. A total of 7 neonates developed bacteraemia (37% attack rate), of whom 3 died (43% case fatality rate). A birth weight < 1500 g was the only statistically significant risk factor.
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