Publications by authors named "Efren Avendano-Tamayo"
Article Synopsis
- Estuarine sediments store materials from land and provide insights into regional human activities and natural processes over time.
- This study analyzes the relationship between the geochemical composition of various metals in sediments and factors like precipitation, land use, and oceanographic changes in a Caribbean gulf spanning around 1,000 years.
- Findings indicate moderate enrichment of metals, particularly showing that certain metal contents correlate with sediment characteristics, while a rising trend in granulometry suggests increased sediment transport energy in recent times.
Article Synopsis
- A new Y-STR multiplex called CombYplex was developed, along with a machine learning program named PredYMaLe, to predict haplogroups while meeting forensic standards.
- The CombYplex consists of two sub-panels (M1 and M2) focused on different mutation rates, and testing showed it effectively distinguishes haplogroup classes from a sample of 996 individuals.
- The machine learning models SVM and Random Forest achieved high prediction accuracy (around 97%), although some haplogroups had lower scores due to small sample sizes, highlighting the importance of a large and diverse training dataset for improving classification accuracy.
Introduction: Host genetics is recognized as an influential factor for the development of dengue disease.
Objective: This study evaluated the association of dengue with the polymorphisms rs8192284 for gene IL6R, rs3775290 for TLR3, and rs7248637 for DC-SIGN.
Materials And Methods: Of the 292 surveyed subjects, 191 were confirmed for dengue fever and the remaining 101 were included as controls.
Introduction: The genetic makeup of the host contributes to the clinical profile of dengue. This could be due to the effect of variants in the genes encoding pro-inflammatory cytokines.
Objective: To evaluate the association between the variants of three polymorphisms in TNFA, IL6 and IFNG candidate genes with dengue severity in a sample of Colombian population.
Article Synopsis
- The transatlantic slave trade resulted in the largest forced migration in history, but the genetic backgrounds of enslaved Africans and their descendants are not well understood.
- Researchers analyzed genetic data from 107 African-descendant individuals in South America and 124 individuals from West Africa, revealing significant differences in ancestral proportions among these populations.
- The study found that the Noir Marron population has the highest African ancestry (∼98%) due to genetic isolation, while Brazilian and Colombian populations display more European and Native American ancestry linked to historical events of European admixture, as well as unique genetic connections to specific African regions.