Overexpression of , , and in Circulating Tumor Cells Derived from Patients with DLBCL Decreases Event-Free Survival.

Purpose: Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous malignant lymphoid neoplasm and is the most common subtype of non-Hodgkin lymphoma in adults. More than half of patients with DLBCL can achieve remission with standard R-CHOP regimes; however, approximately 30-40% of patients are still failing this standard therapy, which remains as an important cause of progression and mortality of this disease. It is necessary to have diagnostic and monitoring tools that allow us to improve the accuracy of prognosis in these patients.

Experiences with health care and health-related quality of life of patients with hematologic malignancies in Mexico.

Background: In Mexico, patients with hematologic malignancies (HMs) are characterized by being at high risk and advanced stages at diagnosis and by having a low cure rate; yet information on their experiences with health care and health-related quality of life (HRQL) is scarce. We aimed to evaluate experiences with health care and HRQL of patients with HMs and the association between these patient-reported measures.

Methods: We conducted a cross-sectional survey in two public oncology hospitals in Mexico City.

Iron Chelation in Transfusion-Dependent Patients With Low- to Intermediate-1-Risk Myelodysplastic Syndromes: A Randomized Trial.

Background: Iron chelation therapy (ICT) in patients with lower-risk myelodysplastic syndromes (MDS) has not been evaluated in randomized studies.

Objective: To evaluate event-free survival (EFS) and safety of ICT in iron-overloaded patients with low- or intermediate-1-risk MDS.

Design: Multicenter, randomized, double-blind, placebo-controlled trial (TELESTO).

Acute Leukemia Characteristics are Different Around the World: the Mexican Perspective.

Background: The incidence of acute leukemia (AL) has increased. Its prognosis is variable and depends on several baseline characteristics with a highly heterogeneous presentation. In Mexico, large-scale descriptive studies have not yet been published; the objective of this study was to analyze the initial basic characteristics of patients diagnosed with AL in our population.

[Acute leukemia frequency observed in a reference hospital].

Objective: to compare the frequency of acute leukemia in two periods of study in a reference Hospital at Mexico City.

Methods: it was an observational study. There were registered 250 cases with the morphology diagnostic criterion of acute leukemia.