Publications by authors named "Efrat Chorna"
Background: Advances in treatment could mitigate the expected adverse changes in the body composition of children and adolescents with type 1 diabetes (T1D).
Objectives: To examine the evolution of weight status and body composition and their association with glycaemic control and partial clinical remission in youth with T1D.
Methods: Ninety-nine participants with T1D (median age 9.
Article Synopsis
- The study explores the use of liraglutide, a GLP-1 analogue, as an off-label therapy for patients with rare genetic causes of early-onset obesity and related complications.
- Three case studies demonstrated that liraglutide can significantly halt weight gain, improve metabolic parameters, and support overall health in affected individuals despite their complex genetic backgrounds.
- The findings suggest that liraglutide may have broader benefits beyond weight loss, making it a potentially valuable treatment option for managing obesity-related conditions in genetically predisposed patients.
Background: Women with type 1 diabetes (T1D) are more susceptible than men to cardiovascular disease (CVD). Signs of increased risk may already appear among adolescent girls.
Objectives: We explored the contribution of body composition to the development of CVD risk factors among youth with T1D.
Aims: The precision medicine approach of tailoring treatment to the individual characteristics of each patient has been a great success in monogenic diabetes subtypes, highlighting the importance of accurate clinical and genetic diagnoses of the type of diabetes. We sought to describe three unique cases of childhood-onset diabetes in whom skeletal manifestations led to the revelation of a rare type of diabetes. METHODS : Case-scenarios and review of the literature.
View Article and Find Full Text PDFAims: Children with chronic diseases were unable to receive their usual care during COVID-19 lockdown. We assessed the feasibility and impact of telehealth visits on the time-in-range (TIR) of paediatric individuals with type 1 diabetes (T1D).
Methods: An observational multicentre real-life study.
Aims: Disparities in health outcomes in pediatric type 1 diabetes (T1D) based on race/ethnicity and socioeconomic position (SEP) have been reported. We compared T1D characteristics between Eritrean status-less children living in Israel and native-born Israeli children.
Methods: This observational study compared 7 Eritrean and 28 Israeli children (< 8 years old at T1D diagnosis) who were diagnosed in a single diabetes center during 2015-2019.
Background: Younger age at diagnosis of type 1 diabetes (T1D) may affect the clinical course and outcome. We examined whether age at diagnosis was associated with glycemic control and metabolic outcome in young adulthood.
Methods: This observational study included 105 young adults with T1D (current mean age: 21.
To describe patient characteristics at presentation, management, and fertility preservation rates among a cohort of Israeli children and adolescents with gender dysphoria (GD). We performed a retrospective chart review of 106 consecutive children and adolescents with GD (<18 years) referred to and followed at the multidisciplinary Israeli Pediatric Gender Dysphoria Clinic from March 2013 through December 2018. Of the 106 patients, 10 were prepubertal (9 prepubertal transgender females), and 96 were pubertal (38 pubertal transgender females).
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