Publications by authors named "Efietngab Atembeh Noura"

Rift Valley fever (RVF) is a severe zoonotic mosquito-borne disease that represents an important threat to human and animal health, with major public health and socioeconomic impacts. This disease is endemic throughout many African countries and the Arabian Peninsula. This systematic review with meta-analysis was conducted to determine the RVF prevalence in humans, mosquitoes and other animal species in Africa.

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Background: Fruits and vegetables are very important for human diet as they provide all the nutrients needed to be healthy with just a daily-recommended intake of 400 to 600 mg. However, they constitute one of the major sources of human infectious agents. Thus monitoring of the microbial contaminants of the fruits and vegetables is very crucial for human safety.

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A substantial amount of epidemiological data has been reported on Enterovirus D68 (EV-D68) infections after the 2014 outbreak. Our goal was to map the case fatality rate (CFR) and prevalence of current and past EV-D68 infections. We conducted a systematic review (PROSPERO, CRD42021229255) with published articles on EV-68 infections in PubMed, Embase, Web of Science and Global Index Medicus up to January 2021.

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Introduction: Africa denotes unique facies for hepatocellular carcinoma (HCC) characterized by a conjunction of low sensitization, restricted access to diagnosis and treatment and associated with the highest incidence and mortality in the world. We investigated whether hepatitis B (HBV), C (HCV) and D (VHD) viruses were etiological agents of HCC in Africa.

Methods: Relevant articles were searched in PubMed, Web of Science, African Index Medicus, and African Journal Online databases, as well as manual searches in relevant reviews and included articles.

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Article Synopsis
  • The systematic review aimed to assess the relationship between diabetes mellitus (DM) and the risk of developing tuberculosis (TB), addressing confounders like age, gender, and lifestyle factors that previous studies may have overlooked.
  • A total of 12,796 articles were screened, leading to the inclusion of 47 observational studies with over half a million DM or TB cases, and results indicated a significant association with an odds ratio of 2.3, meaning diabetics were more than twice as likely to develop TB compared to non-diabetics.
  • The study confirmed that the increased TB risk persisted across various study types (cohort, case-control, cross-sectional) and was influenced by geographic differences, though the statistical significance remained consistent
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  • Hepatitis B virus (HBV) is a major global health issue, impacting around 2 billion people and causing about 1 million deaths annually, with healthcare workers (HCWs) at high risk due to potential exposure to infected blood.
  • This study aims to assess the global prevalence of HBV serological markers among HCWs by analyzing relevant research published between 1970 and 2019, including a total of 227 studies from 71 countries.
  • The meta-analysis revealed a pooled prevalence of current HBV infection (2.3%), with very low rates for HBeAg (0.2%) among the HCW population, highlighting the importance of monitoring and improving HBV control strategies in healthcare settings.
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Preeclampsia is one of the most common complications of pregnancy and occurs in approximately 3-8% of all pregnancies worldwide. Although the aetiology of preeclampsia still largely remains unclear, it is thought to be related to endothelial dysfunction and can lead to serum lipid abnormalities. Therefore, this case-control study was conceived and designed with the aim to compare maternal lipid profile parameters and cardiovascular risk factors, between preeclamptic and healthy pregnancies.

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Rabies is transmitted to humans mainly by dogs but also by other animal species. Reliable data on the incidence of Rabies virus (RABV) in humans, dogs, and other animal species in Africa, could be essential in the implementation of a global strategic plan to eliminate the RABV by 2030 as adopted by the WHO, OIE, and FAO. We searched the Pubmed, Embase, Scopus, African Journal Online, and African Index Medicus databases for relevant studies that report data on the incidence of RABV in Africa up to February 17, 2020.

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There are uncertainties about the global epidemiological data of infections due to Crimean-Congo hemorrhagic fever virus (CCHFV). We estimated the global case fatality rate (CFR) of CCHFV infections and the prevalence of CCHFV in humans, ticks and other animal species. We also explored the socio-demographic and clinical factors that influence these parameters.

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Article Synopsis
  • The researchers analyzed data from various databases spanning from 1969 to 2020, ultimately reviewing 109 reports which contributed to 291 prevalence records across 25 countries.
  • The overall CFR for humans was found to be 29.7%, with a pooled prevalence of 8.7% in humans, 3.2% in rodents, and 0.7% in other mammals, indicating significant regional disparities and higher risks in Western Africa.
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