Publications by authors named "Efi Kouri"
The goals of this study were to detect the numerical alterations of chromosomes 1 and 7 in breast cancer and to correlate the findings with DNA ploidy status as well as with parameters of prognostic significance. Fluorescence in situ hybridization (FISH) with centromeric probes for chromosomes 1 and 7 and cellular DNA content measurement by image analysis-based cytophotometry were applied on interface nuclei from fresh tissue imprints of 59 breast ductal carcinomas. Immunohistochemical stainings for estrogen receptor (ER), progesterone receptor (PR), HER-2, p53, and Ki67 were performed on paraffin tumor sections.
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- Cystosarcoma phyllodes (CP) is a rare breast tumor characterized by both benign epithelium and spindle cell stroma, and its biological behavior is difficult to predict solely from appearance.
- The study examined immunohistochemical markers such as bFGF, urokinase, Ki67, and p53 in 14 low-grade CP (LCP) and 9 high-grade CP (HCP), finding that certain markers like bFGF and Ki67 were more frequently positive in high-grade tumors.
- Results suggest that epithelial-stromal interactions play a role in CP development, highlighting the epithelium's importance in the tumor's biological behavior.