Mutational analysis in drug resistant Mycobacterium tuberculosis in Western Uttar Pradesh.

Background: Multi-drug resistant tuberculosis (MDR-TB) results in treatment failure and poor clinical outcomes. This study was carried out with the aim to determine the pattern of drug resistance against Mycobacterium tuberculosis towards first line ATT (anti-tubercular treatment) in sputum smear-positive patients using Line Probe Assay (LPA).

Methods: A cross sectional prospective study was carried out in a tertiary care Hospital of Meerut.

Vitamin D and COVID-19 - Let's Explore the Relationship!

Vitamin D plays a protective role against COVID-19. Patients with deficiency of vitamin D are more prone to severe SARS-CoV-2 infections. It is known to enhance human β-defensin 2 and antimicrobial peptide.