Publications by authors named "Edzard von Knyphausen"
The purpose of this study was to review the outcome of pediatric heart recipients with uncorrectable congenital heart disease, failed corrective procedures, or intractable acquired cardiomyopathy. Between 1988 and 2005, cardiac transplantations were performed in 128 pediatric patients (59 girls and 69 boys) at the Heart-Center North-Rhine-Westphalia. Their ages varied between 1 week and 18 years (mean, 7.
View Article and Find Full Text PDFEnd-stage congenital heart disease (CHD) is an important indication for pediatric heart transplantation (HTx) as well as transplantation in adult populations. The purpose of this retrospective analysis was to compare the survival rate of adults who underwent HTx for end-stage CHD with those who underwent HTx for other causes. To find out whether HTx is a viable therapeutic option for adult patients with preoperated CHD, data from 15 adult patients with different forms of CHD, who had previously undergone different corrective and palliative procedures, were retrospectively analyzed and compared with the HTx data of 1400 adult patients (>15 years old) whose indications for HTx were other than end-stage CHD.
View Article and Find Full Text PDFObjective: We retrospectively reviewed 104 consecutive patients who underwent orthotopic heart transplantation between November 1989 and February 2004.
Patients And Methods: From November 1989 to February 2004, the total number of heart transplantations were 1,340 cases at our institute. One hundred four (7.
Mechanical ventricular circulatory support in children; Bad Oeynhausen experience.
Ann Thorac Cardiovasc Surg
October 2005
Article Synopsis
- Mechanical circulatory support systems are increasingly used in pediatric patients, but their size limits their deployment for smaller children; this report discusses implantation experiences with such devices.
- A total of 29 pediatric patients received various mechanical support devices (including LVAD, BVAD, and ECMO) over a period from 1987 to 2004, with support durations averaging 32.3 days; although 10 children successfully underwent heart transplants, there were significant complications and 16 fatalities during support.
- There is a need for the development of smaller, more durable assist devices for children, as ongoing research and clinical applications continue in this area.