Investigation of bioprintable modified agar-based hydrogels with antimicrobial properties.

Due to the numerous dangers arising from excessive use of antibiotics in treatments, researchers have been searching for natural alternatives to conventional antibiotics. Despite the popularity of plant extracts, essential oils, and their derivatives in herbal medicine, their applications in novel therapies are rather limited. This paper tries to open a new possibility for infection treatments by assessing the suitability of antimicrobial hydrogels as bioinks.

Investigation on Swelling of Agar-Based Antibacterial Hydrogels for Hard-to-Heal Wound Dressings.

Despite a wide range of available wound treatments, hard-to-heal wounds still pose a challenge. Hydrogels are often used as dressings for these wounds, because they sustain moisture in the wound environment, supporting the natural healing process. However, it is still not fully understood how physicochemical properties of hydrogel matrix affect the drug release process.

Recent advances in 3D bioprinted tumor models for personalized medicine.

Cancerous tumors are among the most fatal diseases worldwide, claiming nearly 10 million lives in 2020. Due to their complex and dynamic nature, modeling tumors accurately is a challenging task. Current models suffer from inadequate translation between in vitro and in vivo results, primarily due to the isotropic nature of tumors and their microenvironment's relationship.

Polyurethane based hybrid ciprofloxacin-releasing wound dressings designed for skin engineering purpose.

Purpose: Even in the 21st century, chronic wounds still pose a major challenge due to potentially inappropriate treatment options, so the latest wound dressings are hybrid systems that enable clinical management, such as a hybrid of hydrogels, antibiotics and polymers. These wound dressings are mainly used for chronic and complex wounds, which can easily be infected by bacteria.

Materials And Methods: Six Composite Porous Matrices (CPMs) based on polyurethane (PUR) in alliance with polylactide (PLAs) and poly(vinyl alcohol) (PVA) were prepared and analyzed using optical microscopy.