Publications by authors named "Edwin J Bunggulawa"
Article Synopsis
- Breast cancer is the most common cancer among women and a leading cause of cancer-related deaths, prompting research into better treatment options.
- Recent developments in immunotherapy, especially with hydrogels, show promise for enhancing patient survival rates by offering targeted and less toxic treatments.
- This review focuses on the benefits and workings of hydrogels in breast cancer immunotherapy, including their ability to alter the tumor environment and deliver drugs effectively, suggesting they could lead to more personalized and effective treatments for patients.
Triple-negative breast cancer (TNBC) is a breast cancer subtype that does not express the estrogen receptor, the progesterone receptor, or the human epidermal growth factor receptor 2 and that is characterized by high invasiveness, high metastatic potential, and poor prognosis. TNBC lacks receptors and hence cannot be treated by using targeted therapies; as such, the therapeutic potential of Indonesian herbal plants against this disease is worth exploring. Herein, we explore the molecular docking and the molecular dynamics simulations of α-mangostin on glycogen synthase kinase 3β (GSK3β; PDB ID: 4ACC).
View Article and Find Full Text PDFRecent advancements in the use of exosomes as drug delivery systems.
J Nanobiotechnology
October 2018
Extracellular vesicles (EVs) are the substances that are released by most types of cells and have an important role in cell to cell communication. Among the most highly researched EVs are exosome. Recent studies show that exosomes derived from cells have different roles and targets.
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