Publications by authors named "Edwin Cunningham"
Article Synopsis
- Neuroendoscopic surgery often suffers from poor stereoscopic vision and image quality, but image-guided endoscopy (IGE) and image-guided surgery (IGS) might solve these issues.
- The study assessed the feasibility of IGE by tracking a rigid endoscope in 14 patients with various neurological conditions, with no reported complications and high accuracy compared to traditional methods.
- The findings suggest IGE could enhance neurosurgery and might be applicable to other areas beyond the central nervous system.
Article Synopsis
- Neurovascular complications from carotid artery stenting (CAS) can include issues like embolism, hemorrhage, dissection, thrombosis, and vasospasm.
- Effective management of these complications necessitates understanding of vascular anatomy, accurate identification of complications, and a tailored response plan based on the operator's expertise.
- The chapter outlines strategies for preventing and handling procedural complications associated with CAS.
Brain ischemia is associated with an acute release of pro-inflammatory cytokines, notably TNF-alpha and IL-6 and failure of the blood-brain barrier. Shear stress, hypoxia-hypoglycemia, and blood leukocytes play a significant role in blood-brain barrier failure during transient or permanent ischemia. However, these mechanisms have not been studied as independent variables for in vitro ischemia.
View Article and Find Full Text PDFObject: Cranial nerve injuries, particularly motor nerve injuries, following carotid endarterectomy (CEA) can be disabling and therefore patients should be given reliable information about the risks of sustaining such injuries. The reported frequency of cranial nerve injury in the published literature ranges from 3 to 23%, and there have been few series in which patients were routinely examined before and after surgery by a neurologist.
Methods: The authors investigated the risk of cranial nerve injuries in patients who underwent CEA in the European Carotid Surgery Trial (ECST), the largest series of patients undergoing CEA in which neurological assessment was performed before and after surgery.