Publications by authors named "Edwin Ck Tan"

Objective: To investigate the association between patient-reported experiences with new medication discharge counselling and readmission to hospital or emergency department (ED) visits within 30 days of discharge.

Methods: A retrospective cross-sectional study of patient-reported experiences from 8715 patients who reported being prescribed a new medication at discharge from a public hospital. Completeness of medication counselling was assessed based on (i) explanation of medication purpose, (ii) explanation of medication side effects, (iii) patient involvement in decision to use medication, (iv) provision of contradictory information.

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Background: Medication-related hospitalisations present an opportunity for de-prescribing and simplification of medication regimens. The Medication Regimen Complexity Index (MRCI) is a tool for measuring the complexity of medication regimens.

Objectives: To evaluate whether MRCI changes following medication-related hospitalisations, and to evaluate the relationship between MRCI, length of stay (LOS) in hospital, and patient characteristics.

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Background: Polypharmacy, the use of multiple medications by one individual, may be associated with adverse health outcomes including poor cognition. However, it remains unclear whether a longitudinal relationship exists.

Objectives: To investigate the association between polypharmacy and 3-year cognitive ability in older adults.

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Objectives Psychosocial job strain has been associated with a range of adverse health outcomes. The aim of this study was to examine the association between psychosocial job strain and prospective risk of polypharmacy (the prescription of ≥5 medications) and to evaluate whether coping strategies can modify this risk. Methods Cohort study of 9703 working adults [mean age 47.

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Background: Statins are associated with muscle-related adverse events, but few studies have investigated the association with fall-related hospitalizations among residents of long-term care facilities (LTCFs).

Objective: The objective of the study is to investigate whether statin use is associated with fall-related hospitalizations from LTCFs.

Methods: A case-control study was conducted among residents aged ≥65 years admitted to hospital from 2013 to 2015.

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Background: Alzheimer's disease is the most common form of dementia and is a major contributor to morbidity and mortality in older Australians.

Objective: The aim of this article is to provide an overview of available pharmacological therapies for the symptomatic treatment of Alzheimer's disease.

Discussion: Acetylcholinesterase inhibitors (AChEIs) or memantine may be trialled in people with Alzheimer's disease to delay symptoms of cognitive and functional decline.

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Objectives: Medication-induced hyposalivation can increase the risk for oral complications, including dental caries and tooth loss. This problem is particularly important in people with dementia because of their declining ability to maintain oral care. The objective of this study was to describe the association between the number of xerostomic medications used and tooth loss and restorative and dental preventive treatment in a population of persons with dementia.

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Article Synopsis
  • Pharmacist-led medication reviews are collaborative efforts that aim to identify and fix problems related to medications in community settings.
  • A systematic evaluation of existing reviews from 1995 to 2015 showed that many studies found positive outcomes, particularly regarding diabetes, blood pressure, and cholesterol management.
  • While the reviews support the effectiveness of these medication reviews, there’s a need for more rigorous studies focusing on cost analysis and conflicting results related to hospitalization and mortality.
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Background: Polypharmacy is highly prevalent in residential aged care facilities (RACFs). Although polypharmacy is sometimes unavoidable, polypharmacy has been associated with increased morbidity and mortality.

Objective: To identify and prioritize a range of potential interventions to manage polypharmacy in RACFs from the perspectives of health care professionals, health policy and consumer representatives.

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Aim: To investigate analgesic use and pain in people with and without dementia in Australian residential aged are facilities.

Methods: A cross-sectional study of 383 residents of six residential aged are facilities was conducted. Nurses assessed self-reported and clinician-observed pain.

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