Publications by authors named "Edwige Arnold"
Article Synopsis
- - T cell immune dysfunction is a significant issue in chronic HIV infection, and evaluating this dysfunction requires a method that involves both general and specific activation of T cells.
- - Researchers developed a tunable artificial antigen-presenting cell (aAPC) system using silica microbeads, which showed that adding CD28 co-stimulation to anti-CD3 enhances T cell activation and cytokine production, especially IL-2.
- - CD4 and CD8 T cells from untreated HIV patients displayed altered immune responses with a reduced dependence on CD28, and while antiretroviral therapy helps restore some functions in CD4 T cells, CD8 T cells remain impaired, suggesting persistent dysfunction linked to HIV.
