Minimally invasive surgery is complex and prone to variation not routinely objectively measured. We established an association between skills and patient outcomes. The evolving application of artificial intelligence techniques could assist intraoperative analysis.
View Article and Find Full Text PDFIntroduction: Ibogaine is a psychoactive alkaloid derived from the root bark of the West African shrub . It is not licensed in the United Kingdom but is used by individuals to alleviate drug or alcohol use.
Methods: A retrospective analysis of telephone enquiries involving ibogaine between 1 January 2012 and 31 December 2022 to the United Kingdom National Poisons Information Service was performed.
Allied health clinical educators (AHCEs) are vital to health professional student education and clinical education is often expected in a job role. Communities of practice (CoPs) may be a strategy to meet educator learning needs. A rapid review was conducted to determine the structures, purposes, and outcomes of AHCE CoPs, and barriers or enablers of participation in CoPs.
View Article and Find Full Text PDFPurpose: Proximal humerus fracture dislocations are amongst the most severe proximal humerus injuries, presenting a challenging management problem. The aim of this study was to report on long-term outcomes of management of proximal humerus fracture dislocations.
Methods: Patients with a proximal humerus fracture dislocation managed at a Level 1 trauma centre from January 2010 to December 2018 were included.
Mental illness, affecting one in eight people worldwide, is often exacerbated by stigma-which can result in self-stigmatization, isolation, and loneliness and negatively impact access to health care, education, and social connection. Previous research has found that stigma is best reduced through a combination of education about the stigmatized population and intentional contact with individuals from that population. Studies also note the benefits of community-based, culturally-relevant interventions and cultural experiences such as live music.
View Article and Find Full Text PDFPsychol Sport Exerc
January 2025
The role of executive function (EF) in expert sport performance has become a popular topic in sport and exercise psychology research. Research in this area often adopts the unity/diversity framework of EF (i.e.
View Article and Find Full Text PDFLeukopoiesis is lethally arrested in mice lacking the master transcriptional regulator PU.1. Depending on the animal model, subtotal PU.
View Article and Find Full Text PDFIntroduction: The cerebellum is a common lesion site in persons with multiple sclerosis (PwMS). Physiologic and anatomic studies have identified a topographic organization of the cerebellum including functionally distinct motor and cognitive areas. In this study, a recent parcellation algorithm was applied to a sample of PwMS and healthy controls to examine the relationships among specific cerebellar regions, fall status, and common clinical measures of motor and cognitive functions.
View Article and Find Full Text PDFImproving crop salinity management requires enhanced understanding of salinity responses of leaf and fine-root traits governing resource acquisition, ideally in relation to ion accumulation at intra- or inter-specific levels. We hypothesized that these responses are coupled towards integrated resource conservation for plants under prolonged salt treatment. We tested the hypothesis with a glasshouse experiment on saplings of six contrasting hybrids, subjected to either control or salt treatment (reverse osmosis water versus 3.
View Article and Find Full Text PDFBackground: US Department of Veterans Affairs (VA) eligibility policies now allow comprehensive mental and behavioral health care services to be provided to veterans who received an Other Than Honorable (OTH) discharge upon separation from service. Research has shown a disproportionate mental health burden and elevated rates of criminal-legal involvement among these veterans. Eligibility policy shifts may impact programs and services designed to support veterans with criminal-legal involvement, such as veterans treatment courts.
View Article and Find Full Text PDFObjectives: To assess the feasibility of an intervention of midwifery support for antenatal pelvic floor muscle exercises (PFME) to prevent postnatal urinary incontinence (UI).
Design: Feasibility and pilot cluster randomised controlled trial. Clusters were community midwifery teams.
Background: Neonatal and maternal mortality remains high in low- and middle-income countries (LMIC), especially in sub-Saharan Africa. Quality data collection is crucial to understand the magnitude of these problems and to measure the impact of interventions aimed at improving neonatal and maternal mortality. However, data collection in the low-income country setting, especially in rural areas, has been a challenge for researchers, policy makers, and public health officials.
View Article and Find Full Text PDFThe archaeal class is widely and abundantly distributed in anoxic habitats. Metagenomic studies have suggested that they are mixotrophic, capable of CO fixation and heterotrophic growth, and involved in acetogenesis and lignin degradation. We analyzed 35 metagenome-assembled genomes (MAGs), including the first complete circularized MAG (cMAG) of the Bathy-6 subgroup, from the metagenomes of three full-scale pulp and paper mill anaerobic digesters and three laboratory methanogenic enrichment cultures maintained on pre-treated poplar.
View Article and Find Full Text PDFGrasses are exceptionally productive, yet their hydraulic adaptation is paradoxical. Among C grasses, a high photosynthetic rate (A) may depend on higher vein density (D) and hydraulic conductance (K). However, the higher D of C grasses suggests a hydraulic surplus, given their reduced need for high K resulting from lower stomatal conductance (g).
View Article and Find Full Text PDFThe anatomical reorganization required for C photosynthesis should also impact plant hydraulics. Most C plants possess large bundle sheath cells and high vein density, which should also lead to higher leaf capacitance and hydraulic conductance (K). Paradoxically, the C pathway reduces water demand and increases water use efficiency, creating a potential mismatch between supply capacity and demand in C plant water relations.
View Article and Find Full Text PDFEver since the first description of an inherited immunodeficiency in 1952 in a boy with gammaglobulin deficiency, new insights have progressed rapidly in disorders that are now referred to as inborn errors of immunity. In a field where fundamental molecular biology, genetics, immune signaling, and clinical care are tightly intertwined, 2022-24 saw a multitude of advances. Here we report a selection of research updates with a main focus on (1) diagnosis and screening, (2) new genetic defects, (3) susceptibility to severe coronavirus disease 2019 infection and impact of vaccination, and (4) treatment.
View Article and Find Full Text PDFHydrofluoroolefins (HFOs) and hydrochlorofluoroolefins (HCFOs) are the leading synthetic replacements for compounds successively banned by the Montreal Protocol and amendments. HFOs and HCFOs readily decompose in the atmosphere to form fluorinated carbonyls, including CFCHO in yields of up to 100%, which are then photolyzed. A long-standing issue, critical for the transition to safe industrial gases, is whether atmospheric decomposition of CFCHO yields any quantity of CHF (HFC-23), which is one of the most environmentally hazardous greenhouse gases.
View Article and Find Full Text PDFPurpose: To understand diversity, inclusion, and capacity of genetic counselors (GCs) in Australasia (Australia and New Zealand).
Methods: Individuals with or working toward a GC qualification in Australasia were invited to complete an online survey, between November 2022 and March 2023. Quantitative data were analyzed using descriptive statistics, 1-sample proportion -tests, 2-sample -tests, and χ tests.
Importance: Previous research has examined outcomes among very preterm newborns by the birthing parent's race and ethnicity, but knowledge about these trends during the COVID-19 pandemic is limited.
Objective: To examine trends in outcomes among Black, Hispanic, and Asian preterm newborns compared with White preterm newborns.
Design, Setting, And Participants: This cohort study (2018-2022) took place at 774 neonatal intensive care units in the Vermont Oxford Network.
The optical properties of lobed palisade mesophyll cells remain poorly understood despite their presence in diverse taxa and the critical role of the palisade layer in leaf-light interactions and carbon assimilation. Using micro-computed tomography, 3D ray tracing simulations, and physiological experiments, we tested the interactions between palisade cell geometry, chloroplast localization, light directional quality, and leaf optical and photosynthetic performance in the model taxon Viburnum. Simulations showed that lobed cells shifted between absorptance- or transmittance-dominated states depending on chloroplast localization, irrespective of light directional quality.
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