Publications by Edward-Benedict Brodie of Brodie

Publications by authors named "Edward-Benedict Brodie of Brodie"

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Replication-associated strand asymmetries in mammalian genomes: toward detection of replication origins.

Marie Touchon Samuel Nicolay Benjamin Audit Edward-Benedict Brodie of Brodie Yves d'Aubenton-Carafa

Proc Natl Acad Sci U S A

July 2005

In the course of evolution, mutations do not affect both strands of genomic DNA equally. This imbalance mainly results from asymmetric DNA mutation and repair processes associated with replication and transcription. In prokaryotes, prevalence of G over C and T over A is frequently observed in the leading strand.

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