Cancer imaging informatics workshop report from the Biomedical Imaging Program of the National Cancer Institute.

A group of experts on very large databases, quantitative imaging, data format standards development, image management and communications, and related technologies for cancer imaging met at a recent workshop sponsored by the BIP and discussed the key issues confronting this field. The BIP received recommendations regarding steps that can be taken to advance the technology and take advantage of the opportunities to improve collaboration and utility in cancer imaging. There are tremendous opportunities to change radically the way we use image information.

Phase II study of fludarabine combined with interferon-alpha-2a followed by maintenance therapy with interferon-alpha-2a in patients with low-grade non-hodgkin's lymphoma.

Randomized trials suggest improved disease-free survival in low-grade non-Hodgkin's lymphoma (LGNHL) when interferon is combined with multiagent chemotherapy. This phase II trial was conducted to investigate the feasibility of combining fludarabine monophosphate (fludarabine) and IFN in a regimen for treatment of LGNHL. Twenty-one patients were evaluable.

Factors affecting patient enrollment in radiology clinical trials: a case study of the American College of Radiology Imaging Network.

Rationale And Objectives: This study was designed to identify factors that affect the enrollment of patients into American College of Radiology Imaging Network clinical trials.

Materials And Methods: A quality improvement study was performed. Brainstorming produced an exhaustive list of factors that could affect the interest of sites in participating in American College of Radiology Imaging Network trials, as well as factors that could influence patient recruitment.