Publications by authors named "Edward Tjioe"
Endocrinol Disord
September 2021
Article Synopsis
- The study explores how the placenta affects the metabolism of 3, 3',5-triiodothyronine (T) during late-stage pregnancy in guinea pigs, which reflects similar processes in humans.
- In experiments, researchers found that sulfated 3, 3'-diiodothyronine (TS), a metabolite of T, was transferred from the fetus to the mother, indicating the placenta's crucial role in regulating fetal T levels.
- The findings suggest that specific enzymes in the placenta help protect the developing fetus from excess active thyroid hormone and that TS could be a valuable biomarker for assessing fetal thyroid function in future studies.
