Improved partial k-space reconstruction technique for dynamic myocardial perfusion MRI.

The advent of partially parallel k-space data acquisition and reconstruction techniques has resulted in a drastic reduction in acquisition time. In this work, we have shown that the use of a new hybrid technique for reconstruction of partial k-space data can reduce acquisition time without loss of spatiotemporal resolution. The technique is termed hybrid k-t GRAPPA since it is a combination of k-t GRAPPA and an image-k-space keyhole technique.

Evaluation of three different kinetic models for use with myocardial perfusion MRI data.

Coronary artery disease (CAD), a leading cause of death in the US and worldwide, can be effectively diagnosed and assessed using non-invasive myocardial perfusion MRI. Tracer kinetic models play a crucial role in the analysis and quantification of perfusion. In this work, we evaluate the performance of 3 different kinetic models used to analyze perfusion: (a) a modified 2-compartment model (b) the Johnson-Wilson (JW) model and (c) a modified JW model.