Publications by authors named "Edward Pei-Chuan Huang"

Aims: The PIVOT trial evaluates the clinical outcomes and ventilatory quality of an automatic pneumatic ventilation method compared to a bag-valve-mask ventilation method in patients who have experienced out-of-hospital cardiac arrest and have had an advanced airway placed.

Methods: The PIVOT trial is a pragmatic, open-label, multicenter randomized controlled trial. It aims to recruit 514 patients in Hsinchu County, Taiwan.

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Study Objective: Cardiopulmonary resuscitation (CPR) is critical for out-of-hospital cardiac arrest patients but is prone to rapid changes and errors. Effective teamwork and leadership are essential for high-quality CPR. We aimed to introduce the Airway-Circulation-Leadership-Support (A-C-L-S) teamwork model in the emergency department (ED) to address these challenges.

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Article Synopsis
  • DACPR (dispatcher-assisted cardiopulmonary resuscitation) significantly boosts survival rates for patients experiencing out-of-hospital cardiac arrest, but its effectiveness can differ based on the location of the incident (home vs public place).
  • A study analyzing 1,160 OHCA cases in Taichung City found that public places had younger and predominantly male patients, but lower rates of chest compressions (41.1% vs 65.5% in homes) and a longer time to recognize the OHCA (108 seconds vs 79 seconds).
  • Public callers faced more physical barriers and were more likely to refuse guidance during emergencies compared to private home callers, who experienced higher OHCA recognition and more successful implementation
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Background And Introduction: In comparison to other physical assessment methods, the inconsistency in respiratory evaluations continues to pose a major issue and challenge.

Objectives: This study aims to evaluate the difference in the identification ability of different breath sound.

Methods/description: In this prospective study, breath sounds from the Formosa Archive of Breath Sound were labeled by five physicians.

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Objectives: The quality of prehospital resuscitation provided by emergency medical technicians (EMTs) is essential to ensure better outcomes following out-of-hospital cardiac arrests (OHCA). We assessed the quality of prehospital resuscitation by recording time to key prehospital interventions using EMT-worn video devices and investigated its association with outcomes of patients with OHCA.

Methods: This retrospective, cross-sectional study included cases of non-traumatic OHCA in adults treated by emergency medical services (EMS) in Hsinchu City, Taiwan, during 2022 and 2023.

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Article Synopsis
  • Out-of-hospital cardiac arrest (OHCA) is a significant public health concern, and understanding heart function before the event can help predict outcomes, but the role of echocardiography in this context is not fully explored.
  • This study aimed to determine how left ventricular ejection fraction (LVEF) measured before OHCA correlates with survival after hospital discharge, using data from a large cohort of adult patients in Taiwan.
  • Findings showed that higher pre-arrest LVEF is linked to better survival rates; for instance, patients with LVEF > 60% had more than five times the odds of surviving to discharge compared to those with LVEF < 40%.
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Video-assisted thoracoscopic surgery (VATS) has been widely used for low invasiveness and shorter recovery time. However, patients receiving VATS still experienced moderate-to-severe pain even under both regional and systemic analgesia. Little is known on the effect of non-pharmaceutical method with physical stabilization for post-VATS pain control.

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Background: The survival trend and factors influencing short- and mid-term mortality in Asian out-of-hospital cardiac arrest (OHCA) survivors should be elucidated. We performed survival analyses on days 3 and 30, hypothesizing decreased survival rates within the initial 3 days post-resuscitation. Additionally, variables linked to mortality at these two timepoints were examined.

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Objectives: Few reports have indicated the secular trend in the sudden cardiac death (SCD) incidence and pre-arrest comorbidities. This study aimed to comprehensively analyze the trend of SCD incidence and its association with pre-arrest comorbidities.

Methods: This population-based cohort study analyzed Taiwan's National Health Insurance (NHI) research database and identified SCD incidents by inspecting data from all emergency department visits from 2011 to 2018.

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Article Synopsis
  • * Conducted as a cluster randomised controlled trial in Taipei City, Taiwan, with participation from advanced life support ambulance teams between July 2020 and June 2023, excluding a temporary halt due to the covid-19 pandemic.
  • * Results showed no significant difference in survival rates; 10.7% of intraosseous patients and 10.3% of intravenous patients were discharged alive, with similar outcomes for return of spontaneous circulation and neurological recovery.
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Purpose: This study aimed to assess the prevalence and factors of physical, psychological, and social frailty among older adults in the emergency department, comparing these data with community population to understand emergency setting manifestations.

Methods: Conducted at the Emergency Department of National Taiwan University BioMedical Park Hospital, this prospective observational cohort study enrolled older adult patients over a three-month period. Frailty assessments included the Study of Osteoporotic Fractures scale for physical frailty, the Tilburg Frailty Indicator for psychological frailty, and the Makizako Social Frailty Index for social frailty.

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Article Synopsis
  • The study investigates the relationship between patients' main complaints and the outcomes of CT scans when they return to the emergency department (ED) within 72 hours after being discharged.
  • Over three years, researchers analyzed data from 7,699 adult patients, finding that 15.6% underwent CT scans, with abdominal pain being the most common complaint associated with positive results.
  • The results indicate that certain chief complaints, particularly gastrointestinal symptoms, significantly increase the chances of finding positive CT results, suggesting that physicians should factor these complaints into their decision-making process when using CT.
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Background: High-risk emergency department (ED) revisit is considered an important quality indicator that may reflect an increase in complications and medical burden. However, because of its multidimensional and highly complex nature, this factor has not been comprehensively investigated. This study aimed to predict high-risk ED revisit with a machine-learning (ML) approach.

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Background: Studies have established that sex and age influence outcomes following out-of-hospital cardiac arrest (OHCA). However, a knowledge gap exists regarding their interaction. This study aimed to investigate the interaction of age and sex and how they cooperatively influence OHCA outcomes.

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Background And Importance: This study compared the on-scene Glasgow Coma Scale (GCS) and the GCS-motor (GCS-M) for predictive accuracy of mortality and severe disability using a large, multicenter population of trauma patients in Asian countries.

Objective: To compare the ability of the prehospital GCS and GCS-M to predict 30-day mortality and severe disability in trauma patients.

Design: We used the Pan-Asia Trauma Outcomes Study registry to enroll all trauma patients >18 years of age who presented to hospitals via emergency medical services from 1 January 2016 to November 30, 2018.

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Objective: This study aims to describe out-of-hospital cardiac arrest (OHCA) characteristics and trends before and during the coronavirus disease-2019 (COVID-19) pandemic in Taiwan.

Methods: We conducted a retrospective cohort study using a 5-year interrupted time series analysis. Eligible adults with non-traumatic OHCAs from January 2017 to December 2021 in 3 hospitals (university medical center, urban second-tier hospital, and rural second-tier hospital) were retrospectively enrolled.

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Article Synopsis
  • The study investigates risk factors for missed acute cardiovascular emergencies in patients who returned to the emergency department (ED) after initially presenting with chest pain.
  • It included 453 adult patients, identifying that 13.2% were later diagnosed with acute cardiovascular conditions upon revisits.
  • Key risk factors for these emergencies were found to be male gender, abnormal ECG rhythms, and significant increases in high sensitivity Troponin-T levels during follow-up, indicating the need for heightened awareness in ED evaluations.
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Background: Bacteremia is a severe complication of infectious disease. Patients with a high bacteremia risk in the emergency department (ED) but misidentified would lead to the unscheduled revisits. This study aimed to develop a simplified scoring model to predict bacteremia in patients with unscheduled ED revisits.

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Background: Data about changes in the characteristics of ED return visits before and after the COVID-19 outbreak are limited. This study aimed to report the differences on utility in ED return visits after the COVID-19 outbreak.

Methods: This retrospective cohort study was conducted from 2019 to 2020.

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Background: This study aimed to investigate the association between the carotid ultrasound results and 1-yr mortality of patients with neurological deficits in the emergency department (ED).

Methods: This study included patients with neurological symptoms who presented to the ED between January 1, 2009 and December 31, 2018, and underwent sonographic imaging of the bilateral carotid bulb, common carotid artery (CCA), internal carotid artery (ICA), and external carotid arteries. A stenosis degree of >50% was defined as significant carotid stenosis.

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In-hospital cardiac arrest (IHCA) in the emergency department (ED) is not uncommon but often fatal. Using the machine learning (ML) approach, we sought to predict ED-based IHCA (EDCA) in patients presenting to the ED based on triage data. We retrieved 733,398 ED records from a tertiary teaching hospital over a 7 year period (Jan.

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