Publications by authors named "Edward Ofori Akwafo"
Article Synopsis
- Medium-chain-length fatty alcohols are valuable in various industries, including surfactants, lubricants, and cosmetics, with their acetate esters commonly used in flavors and fragrances.
- Researchers engineered strains of Pseudomonas putida to enhance its ability to produce 1-hexanol and hexyl acetate by removing genes responsible for degrading fatty alcohols.
- The optimal engineered strain produced significant amounts of 1-hexanol and hexyl acetate, suggesting P. putida can be developed as a microbial factory for sustainable production of medium-chain-length fatty alcohols and their products.
Background: Medium-chain-length α,ω-diols (mcl-diols) are important building blocks in polymer production. Recently, microbial mcl-diol production from alkanes was achieved in E. coli (albeit at low rates) using the alkane monooxygenase system AlkBGTL and esterification module Atf1.
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