Publications by authors named "Edward Jierjian"

Article Synopsis
  • The study examines the safety and effectiveness of onabotulinumtoxinA (a type of Botox) for treating platysma prominence (PP), which affects the definition of the jawline and creates vertical neck bands.
  • Participants with moderate to severe PP received either the treatment or a placebo, and the outcomes were monitored for 120 days.
  • Results showed significantly more improvement in those receiving onabotulinumtoxinA compared to the placebo group, leading to better jawline definition and reduced psychosocial impact from PP symptoms.*
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Background: Platysma prominence (PP) refers to the undesirable effects that may occur with platysma muscle contraction.

Objective: Evaluate safety and efficacy of onabotulinumtoxinA for improving Moderate (Grade 3) to Severe (Grade 4) PP in adults.

Methods: Participants were randomized 1:1 to receive a total dose of onabotulinumtoxinA 26, 31, or 36 U or placebo on Day 1 and monitored for 120 days.

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Our purpose was to determine if docusate monotherapy is effective in preventing opioid-induced constipation in patients receiving opioids following orthopedic surgery. Our single-center, retrospective, cohort study evaluated 212 orthopedic patients who received opioids between May 1, 2018, and December 31, 2018. All patients were aged 18 years and older, hospitalized for more than 48 hours, and received docusate for primary prevention of constipation post-operatively.

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