Publications by authors named "Edward J"

Purpose: The objective of the current study is to introduce a proposed method and evaluate its efficacy using the greater trochanter (GT) tip rather than the lesser trochanter (LT) as an anatomical landmark to reduce leg length discrepancy (LLD) during performance of hip arthroplasty.

Materials And Methods: Thirty-two patients who underwent hip arthroplasty were divided according to the GT group (n=17) and the LT control group (n=11); four patients were excluded. LLD was determined by assessing the vertical lengths parallel to the line connecting the lower margin of the teardrop to the most prominent part of the LT on a standing anteroposterior pelvic X-ray taken 30 days after the procedure.

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Exercise testing is frequently incorporated into management of patients with cardiovascular and/or pulmonary disease. A lifelong commitment to exercise promotes cardiac remodeling, leading to changes in structure and function of the atria and ventricles, commonly referred to as the "athletic heart." Stress testing is also incorporated into the management of athletes for a variety of reasons, such as identifying the cause of exertional symptoms, determining level of fitness and training zones, or assessing for acquired cardiomyopathies.

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Introduction: This study evaluated the impact of Financial and Insurance Navigation Assistance-Training - a pilot interprofessional training program to facilitate cost of care (CoC) conversations and address health-harming social determinants of health in a pediatric hematology-oncology clinic.

Methods: A pre-post study design was used to evaluate the impact of Financial and Insurance Navigation Assistance-Training on an interprofessional health care team's (clinicians, social workers, financial navigator, and legal advocates) knowledge, attitudes, and behaviors related to CoC conversations and screening, referring, and collaborating with interprofessional team members. Data were collected via surveys administered at baseline/pretraining, immediate post-training, and 12-month post-training.

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Considerable efforts have been devoted to addressing the problem of conflicts of interest (COI) in health research, policy, education, and practice. An overwhelming body of evidence demonstrates that conflicts associate with deleterious outcomes for the biomedical research enterprise. Nevertheless, little has changed for research, specifically, since the Institute of Medicine's landmark was published over a decade ago.

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  • Disparities in heart failure care quality contribute to varying patient outcomes based on sex, race, ethnicity, and insurance type among hospitalized patients.
  • A study analyzed data from 685,227 patients across 596 hospitals, finding that women generally received worse quality of care than men, but some differences disappeared after adjusting for individual patient factors.
  • Racial and ethnic minorities often performed as well or better than White and insured patients, but specific treatment measures showed significant gaps, particularly for certain groups like Asian, Hispanic, and Black patients, highlighting within-hospital variations and a need for improvement in care equity.
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  • The study aimed to assess how a patent foramen ovale and fibroblast growth factor-21 affect core temperature changes in SCUBA divers, while also examining the impact of wetsuit thickness and body measurements on these temperature shifts.
  • Involving 31 divers, the research found no significant effect of the patent foramen ovale on temperature responses during dives or on fibroblast growth factor-21 levels.
  • Results indicated that the combination of wetsuit thickness and individual body characteristics, like body mass and surface area, plays a significant role in regulating core temperature during diving.
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infections have been associated with cardiovascular complications, including myocarditis and myopericarditis. This presentation of myopericarditis highlights key clinical features to aid in diagnosis and the importance of prompt treatment with antibiotics, colchicine and non-steroidal anti-inflammatory drugs (NSAIDs).

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Introduction: Residents of Appalachian regions in Kentucky experience increased colorectal cancer (CRC) incidence and mortality. While population-based screening methods, such as fecal immunochemical tests (FITs), can reduce many screening barriers, written instructions to complete FIT can be challenging for some individuals. We developed a novel audiovisual tool ("talking card") to educate and motivate accurate FIT completion and assessed its feasibility, acceptability, and efficacy.

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Introduction: High tibial osteotomy (HTO) is a surgery performed to treat the symptoms and prevent the progression of medial osteoarthritis. Post-operative bleeding has led to early returns to hospital following surgery. Intrafocal injection of tranexamic acid (TXA) could reduce this bleeding complication.

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Background: Pediatric, adolescent, and young adult patients with cancer and their caregivers are at high risk of financial toxicity, and few evidence-based oncology financial and legal navigation programs exist to address it. We tested the feasibility, acceptability, and preliminary effectiveness of Financial and Insurance Navigation Assistance, a novel interdisciplinary financial and legal navigation intervention for pediatric, adolescent and young adult patients and their caregivers.

Methods: We used a single-arm feasibility and acceptability trial design in a pediatric hematology and oncology clinic and collected preintervention and postintervention surveys to assess changes in financial toxicity (3 domains: psychological response/Comprehensive Score for Financial Toxicity [COST], material conditions, and coping behaviors); health-related quality of life (Patient-Reported Outcomes Measurement Information System Physical and Mental Health, Anxiety, Depression, and Parent Proxy scales); and perceived feasibility, acceptability, and appropriateness.

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A team conducted semistructured interviews and developed case reports about financial toxicity (FT) and healthcare transitions (HCTs) with two adolescent and young adult (AYA) cancer survivors. These reports found poor HCTs f.

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Care transition programs can result in cost avoidance and decreased resource utilization. This project aimed to determine whether implementation of a discharge clinic, referral to a community paramedicine program, or a second postdischarge call affected 30-day readmission rates. This single-center retrospective exploratory design study included 727 discharged patients without access to a primary care provider who were scheduled for a discharge clinic transitions appointment.

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Objective: Relatively few dyad-based studies have evaluated the shared psychosocial and financial toxicity (FT) experiences of hematologic patients and their caregivers, especially those undergoing bone marrow transplantations (BMTs). This study evaluated the association of FT with health-related quality of life (QOL) among BMT patient-caregiver dyads.

Methods: Survey and electronic health record data were collected between April 2021 and January 2022 from BMT patients and their caregivers pre- (T1) and post-intervention (T2).

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  • Long COVID affects 25-30% of people who have had SARS-CoV-2, leading to symptoms like extreme fatigue, difficulty in performing daily activities, and rapid heart rate.
  • There is a need for specific treatment strategies to help manage these symptoms, particularly through tailored exercise programs that accommodate the unique challenges faced by Long COVID patients.
  • This review emphasizes that structured exercise can counteract the effects of deconditioning, which often results from prolonged inactivity, and may help reduce the symptom burden in those suffering from Long COVID.
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This study investigates the microplastics (MPs) pollution of the lacustrine ecosystems of Tamil Nadu, South India. It examines the seasonal distribution, characteristics and morphology of MPs and assesses the risk posed by MPs pollution. MPs abundance in the 39 rural and urban lakes studied varies from 16 ± 2.

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We investigated spatiotemporal variations of microplastics (MPs) in Coromandel Coast, Palk Bay, Gulf of Mannar, and West Coast of Tamil Nadu, India. MPs abundance varies from 37 ± 1.52 to 189 ± 9.

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Background: Moral distress occurs when nurses know the ethically correct action to take but are restrained from taking it. Moral distress is prevalent in nurses who work in intense stress situations, as do extracorporeal membrane oxygenation nurses.

Local Problem: Nurses who work in critical care settings have higher levels of moral distress than nurses who work in other practice areas.

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Purpose: This study examined the feasibility, acceptability, and preliminary effectiveness of an oncology financial navigation (OFN) intervention, (), among patients with hematologic cancer and their caregivers who are at increased risk of experiencing financial toxicity (FT).

Methods: All patients who presented to the Division of Hematology and Bone and Marrow Transplant (BMT) at an National Cancer Institute-designated cancer center between April 2021 and January 2022 were screened for FT during inpatient and outpatient visits. Patients who screened positive for FT and met the inclusion criteria were recruited to participate in that provided financial navigation and assistance via a financial navigator.

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  • Exertional dyspnea is a key symptom of heart failure with reduced ejection fraction (HFrEF), but detailed data on how exertion affects heart and lung function is limited.
  • This study involved 35 HFrEF patients, analyzing their cardiovascular and pulmonary responses during exercise to determine how exertion impacts their hemodynamics.
  • The results showed significant increases in pressures in both the right atrium and pulmonary artery during exercise, indicating serious cardiopulmonary dysfunction that affects exercise capacity in patients with HFrEF.
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We present an enantioconvergent access to chiral -heterocycles directly from simple racemic diols and primary amines, through a highly economical borrowing hydrogen annulation. The identification of a chiral amine-derived iridacycle catalyst was the key for achieving high efficiency and enantioselectivity in the one-step construction of two C-N bonds. This catalytic method enabled a rapid access to a wide range of diversely substituted enantioenriched pyrrolidines including key precursors to valuable drugs such as aticaprant and MSC 2530818.

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Background: Cancer care delivery approaches to address financial toxicity among cancer patients are not well-established, especially in rural communities.

Objectives: To identify healthcare staff perspectives of financial toxicity experienced by cancer patients and to examine staff- and systems-level cancer care delivery approaches for addressing financial toxicity, with a focus on rural cancer survivors in Kentucky.

Methods: We conducted key informant interviews using a semistructured interview guide with cancer center staff who provided financial navigation and/or assistance to oncology patients and their caregivers at 15 cancer centers in Kentucky.

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Estuaries are transition zones between freshwater and seawater. There are only few studies on microplastic (MPs) pollution in estuaries. In this study, investigating the spatiotemporal variations of MPs in water, sediment and biota samples of 19 estuaries in Tamil Nadu, India, we assessed the chemical and human exposure risks of MPs.

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  • A 37-year-old athlete underwent a 90 km bicycle test to analyze the pressure and volume in the right ventricle.
  • The test showed that increased pressure in the right ventricle led to decreased efficiency in how the heart and arteries worked together, as well as a drop in cardiac output.
  • To keep up oxygen delivery, the body had to increase the difference between oxygen in the arteries and veins, highlighting how right ventricle performance impacts exercise capacity.
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