Timing the window of implantation by nucleolar channel system prevalence matches the accuracy of the endometrial receptivity array.

Objective: To test if nucleolar channel system (NCS) prevalence matches the accuracy of the endometrial receptivity array (ERA) for identification of the window of endometrial receptivity.

Design: Comparative retrospective study, May 2008-May 2012.

Setting: University-affiliated infertility clinic.

Progesterone Threshold Determines Nucleolar Channel System Formation in Human Endometrium.

Nucleolar channel systems (NCSs), micron-sized organelles specific to nuclei of human endometrial epithelial cells (EECs), are robust markers of the midluteal phase under the apparent control of progesterone. To gain further insight into the role of progesterone in NCS formation, we quantitatively assessed their sensitivity to oral contraceptive pills (OCPs) using immunofluorescence-based detection of NCSs. Comparison of endometrial biopsies and serum progesterone levels on cycle day (CD) 10 and 20 (LH +6/7) of 6 naturally cycling women and 6 OCP users demonstrated that OCPs interfered with NCS formation on CD20, their natural peak presence.

Quantification of nucleolar channel systems: uniform presence throughout the upper endometrial cavity.

Objective: To determine the prevalence of nucleolar channel systems (NCSs) by uterine region, applying continuous quantification.

Design: Prospective clinical study.

Setting: Tertiary care academic medical center.

Implications of blood type for ovarian reserve.

Background: We explored the relevance of blood type to ovarian reserve, as reflected by early follicular phase FSH levels.

Methods: For this cross-sectional observational study, early follicular phase serum levels of FSH (mIU/ml) and estradiol (E2, pg/ml), and information on blood type (A, B, AB and O) and patient age were procured for female patients, ≤ 45 years age (n= 544), who were undergoing fertility evaluation at one of two tertiary care facilities. Serum FSH > 10 mIU/ml was taken to reflect diminished ovarian reserve (DOR).

The continuum of ovarian aging and clinicopathologies associated with the menopausal transition.

The increased length of time that women live after the menopause has provided the impetus for the scientific and public communities to better understand the relationship between ovarian aging and pathologic conditions that present later in life. The maximal size of the ovarian germ cell pool occurs at midgestation and is followed by a continuous decline in oogonia through birth, puberty, the reproductive years, and finally, the menopause. The association between the relative hypoestrogenemia that occurs in the menopausal transition and the symptomatology of that stage of life has been widely studied.

Predictors of chronic disease at midlife and beyond--the health risks of obesity.

A burgeoning pandemic of obesity is well characterized. 41% of U.S.

Parasitic myomas after laparoscopic myomectomy: case report.

Objective: To report a case of a woman who presented with parasitic myomas 27 months after laparoscopic myomectomy.

Design: Case report.

Setting: University medical center.