Publications by authors named "Edward H Zhao"
Article Synopsis
- Glioblastoma (GBM) is a challenging cancer known for its treatment resistance and invasive behavior, leading to recurrence after surgery.
- Researchers screened 22 anti-invasive compounds on GBM cell spheroids to find effective treatments, focusing on their toxicity and ability to inhibit invasion.
- The study highlighted the importance of using both established cell lines and patient-derived organoids to assess treatment efficacy, finding that outcomes can vary significantly due to tumor heterogeneity, suggesting these models might inform personalized cancer therapies.
There is great interest in developing a sensitive method being able to quantitatively measure and compare antioxidant potencies of samples of interest against multiple reactive oxygen species (ROS) whose imbalance could cause oxidative stress. Here, a sensitive nanoprobe, double-stranded DNA encased single-walled carbon nanotubes (SWNTs) has been developed to determine antioxidant potencies of selected samples (caffeine, regular coffee, and decaffeinated coffee) against ROS, hydrogen peroxide, and hydroxyl radicals. Antioxidant vitamin C and uric acid are used as standards.
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