Publications by authors named "Edward G Coker"
Article Synopsis
- This study investigates the immune response differences between active tuberculosis (TB) and latent TB infection (LTBI) to develop better diagnostic methods for distinguishing between the two.* -
- Researchers stimulated blood cells from patients with either active TB or LTBI using specific antigens and analyzed the resulting immune responses through advanced techniques.* -
- Findings revealed that certain types of T cells and cytokines were more prevalent in LTBI compared to active TB, indicating potentially unique immune signatures that could aid in diagnosis.*
Background: Tuberculosis (TB) and COVID-19 are the two leading causes of infectious disease mortality worldwide, and their overlap is likely frequent and inevitable. Previous research has shown increased mortality in TB/COVID-coinfected individuals, and emerging evidence suggests that COVID-19 may increase susceptibility to TB. However, the immunological mechanisms underlying these interactions remain unclear.
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