Publications by authors named "Edward E Dashow"
Background: Antioxidants, particularly vitamin C (ascorbic acid), have the capacity to influence glucose tolerance. Modification of diet could reduce the likelihood of developing gestational diabetes mellitus.
Methods: In a prospective cohort study of pregnant women, we studied the association of maternal plasma ascorbic acid concentrations, measured at an average of 13 weeks' gestation, with subsequent risk of gestational diabetes.
Article Synopsis
- The study aimed to investigate if low vitamin C intake and low plasma ascorbic acid (AA) levels in mothers are linked to a higher risk of gestational diabetes mellitus (GDM).
- Results showed that women with GDM had significantly lower daily vitamin C intake and plasma AA concentrations compared to those without GDM.
- The research indicated that low vitamin C intake (less than 70 mg/day) and low plasma AA concentrations greatly increased the risk of developing GDM, emphasizing the need for further studies on antioxidants' role in pregnancy.
Physical activity has been associated with a reduced risk of gestational diabetes mellitus, but inferences have been hampered by recall and selection bias. The authors examined the relation between recreational physical activity before and during pregnancy and risk of gestational diabetes mellitus in a prospective cohort study. In 1996-2000, 909 normotensive, nondiabetic women in Seattle and Tacoma, Washington, were questioned during early gestation about physical activity performed during the year before and 7 days prior to the interview during pregnancy.
View Article and Find Full Text PDFThe potential benefits and risks of physical activity before and during pregnancy are not well studied. We studied the relation between recreational physical activity and the risk of preeclampsia in a case-control study of 201 preeclamptic and 383 normotensive pregnant women. Participants provided information about the type, intensity, frequency, and duration of physical activity performed during the first 20 weeks of pregnancy and during the year before pregnancy.
View Article and Find Full Text PDFBackground: Oxidative stress plays an important role in the pathophysiology of preeclampsia.
Methods: In a case-control study of 109 women with preeclampsia and 259 controls, maternal dietary and plasma vitamin C in relation to preeclampsia risk were assessed. Dietary intake during the periconceptional period and pregnancy was ascertained using a semiquantitative food frequency questionnaire.