Background: Hepatitis C (HCV) donors are rarely used for cardiac transplantation due to historically poor outcomes. In 2015, nucleic acid testing (NAT) for viral load was added to the routine work-up of organ donors, allowing for the distinction between subjects who remain viremic (HCV Ab/NAT) and those who have cleared HCV and are no longer viremic (HCV Ab/NAT). The American Society of Transplantation recently recommended that HCV Ab/NAT donors be considered non-infectious and safe for transplantation.
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