Publications by authors named "Edward B Cronin"
Article Synopsis
- The study aimed to measure the hemoglobin (Hb) content in breast tumors before starting neoadjuvant chemotherapy, track changes during treatment, and see how these changes correlate with the tumor's response to therapy.
- Patients were monitored using a specialized imaging system over several months, with results graded according to the Miller-Payne system to categorize their response to treatment.
- The findings showed that tumors classified as better responders had higher initial Hb levels and greater changes in Hb content during treatment compared to those classified as non-responders, indicating a potential link between tumor vascularity and treatment effectiveness.
Purpose: To investigate the potential role of optical tomography in the near-infrared (NIR) spectrum with ultrasonographic (US) localization as a means of differentiating early-stage cancers from benign lesions of the breast.
Materials And Methods: The protocol was approved by the institutional review boards and was HIPAA compliant; all participants signed an informed consent. One hundred seventy-eight consecutive women (mean age, 52 years; range, 21-89 years) who underwent US-guided biopsy were imaged with a hand-held probe consisting of a coregistered US transducer and an NIR imager.
Purpose: To investigate prospectively the feasibility of using optical tomography with ultrasonographic (US) localization to differentiate malignant from benign breast masses and to compare optical tomography with color Doppler US.
Materials And Methods: The study was approved by the local internal review board committee and by the Human Subjects Research Review Board of Army Medical Research and Materiel Command. Signed informed consent was obtained, and the study was HIPAA compliant.