Publications by authors named "Edward A Jasion"
Human feasibility study of fluorescence spectroscopy guided optical biopsy needle for prostate cancer diagnosis.
Annu Int Conf IEEE Eng Med Biol Soc
September 2016
Current prostate biopsy cores have a very low diagnostic yield. These biopsies often fail to diagnose prostate cancer since 90% of cores are histopathologically classified as benign. The concentrations of endogenous fluorophores in prostate tissue vary with disease states.
View Article and Find Full Text PDFDiffuse reflectance spectroscopy can differentiate high grade and low grade prostatic carcinoma.
Annu Int Conf IEEE Eng Med Biol Soc
August 2016
Prostate tumors are graded by the revised Gleason Score (GS) which is the sum of the two predominant Gleason grades present ranging from 6-10. GS 6 cancer exclusively with Gleason grade 3 is designated as low grade (LG) and correlates with better clinical prognosis for patients. GS >7 cancer with at least one of the Gleason grades 4 and 5 is designated as HG indicate worse prognosis for patients.
View Article and Find Full Text PDFSystematic diagnosis of prostate cancer using an optical biopsy needle adjunct with fluorescence spectroscopy.
Annu Int Conf IEEE Eng Med Biol Soc
November 2015
Article Synopsis
- Transrectal ultrasound guided prostate biopsies often miss diagnosing prostate cancer, with 90% of samples being benign, highlighting a need for better targeting of cancerous lesions.
- Researchers developed an optical biopsy needle that uses fluorescence spectroscopy to identify cancer by measuring tissue fluorescence before taking samples.
- The study found that this method achieved high sensitivity (86%) and specificity (87%) in distinguishing between benign and malignant tissues, suggesting it could enhance prostate cancer diagnosis and patient care.