Publications by authors named "Edvin Isufi"
Objective: To compare the incidence and natural course of reactive axillary lymph nodes (RAL) between mRNA and attenuated whole-virus vaccines using Deauville criteria.
Methods: In this multi-institutional PET-CT study comprising multiple vaccine types (Pfizer-BioNTech/Comirnaty, Moderna/Spikevax, Sinovac/CoronaVac and Janssen vaccines), we evaluated the incidence and natural course of RAL in a large cohort of oncological patients utilizing a standardized Deauville scaling system (n=522; 293 Female, Deauville 3-5 positive for RAL). Univariate and multivariate analyses were conducted to evaluate the predictive value of clinical parameters (absolute neutrophil count [ANC], platelets, age, sex, tumor type, and vaccine-to-PET interval) for PET positivity.
The translation of AI-generated brain metastases (BM) segmentation into clinical practice relies heavily on diverse, high-quality annotated medical imaging datasets. The BraTS-METS 2023 challenge has gained momentum for testing and benchmarking algorithms using rigorously annotated internationally compiled real-world datasets. This study presents the results of the segmentation challenge and characterizes the challenging cases that impacted the performance of the winning algorithms.
View Article and Find Full Text PDFVaccine-related axillary nodal enlargement is a common benign condition that many mRNA vaccine receivers experience. However, a false attribution of axillary swelling to vaccination may result in delay in cancer care and potential disease progression, particularly in breast cancer patients presenting with ipsilateral axillary lymphadenopathy. We report the case of a 41-year-old pre-menopausal female who presented with suspicious axillary nodal enlargement and a right breast lump (triple-negative invasive ductal carcinoma) after recent administration of the second dose of Moderna mRNA coronavirus disease 2019 (COVID-19) vaccine.
View Article and Find Full Text PDFThis cohort study examines ipsilateral axillary nodal reactivity seen on positron emission tomographic and computed tomographic imaging after intramuscular administration of the coronavirus 2019 mRNA vaccines.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to analyze how the COVID-19 pandemic influenced the use of PET/CT scans from January to June 2020, considering various epidemiological, demographic, and oncological factors.
- - Researchers reviewed 1,685 cases and found a significant 62.5% drop in PET-CT usage during the pandemic's peak, followed by a gradual recovery, influenced by the state's COVID-19 trends.
- - Notable differences emerged in patient demographics and cancer types, with younger patients and minorities experiencing more scans relative to pre-pandemic levels, and hematologic cancers showing less impact than solid tumors.
Objectives: To evaluate the prognostic potential of Lipiodol distribution for the pharmacokinetic (PK) profiles of doxorubicin (DOX) and doxorubicinol (DOXOL) after conventional transarterial chemoembolization (cTACE).
Methods: This prospective clinical trial ( ClinicalTrials.gov : NCT02753881) included 30 consecutive participants with liver malignancies treated with cTACE (5/2016-10/2018) using 50 mg DOX/10 mg mitomycin C emulsified 1:2 with ethiodized oil (Lipiodol).