The front cover artwork is provided by Prof. Björn Corzilius's group at the University of Rostock. The image shows the interference of the isotropic frequency difference between two nuclear spins with the evolution of their dipolar coupling in an MAS rotor.
View Article and Find Full Text PDFMethods which induce site-specificity and sensitivity enhancement in solid-state magic-angle spinning NMR spectroscopy become more important for structural biology due to the increasing size of molecules under investigation. Recently, several strategies have been developed to increase site specificity and thus reduce signal overlap. Under dynamic nuclear polarization (DNP) for NMR signal enhancement, it is possible to use cross-relaxation transfer induced by select dynamic groups within the molecules which is exploited by SCREAM-DNP (Specific Cross Relaxation Enhancement by Active Motions under DNP).
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