The long-term host response to liquid silicone injected during soft tissue augmentation procedures: a microscopic appraisal.

Background: Silicone has a long history of use as a soft tissue filler.

Materials And Methods: As a contribution to the clarification of the role and fate of this material when used as a filler in soft tissue augmentation techniques, 35 skin biopsies were examined by light microscopy. These biopsies were obtained from target areas where liquid silicone had been injected in 25 patients between 1 and 23 years prior, for the correction of depressed scars on the face.

Comparative bioavailability study with two gemfibrozil tablet formulations in healthy volunteers.

Objective: To assess the bioequivalence of gemfibrozil (CAS 25812-30-0) 900 mg tablet formulation from EMS Farmaceutica as test formulation versus a 900 mg tablet formulation as reference in 36 healthy volunteers of both sexes.

Methods: The study was conducted using an open, randomized, two-period crossover design with a 1-week washout interval. Plasma samples were obtained over a 24-h period.