Publications by authors named "Eduardo Serrano-Mora"
Drug Dev Ind Pharm
August 2021
Article Synopsis
- This study introduces a Venturi tube as a static mixer for efficiently creating solid lipid nanoparticles (SLN) from monoolein in a continuous recirculation setup.
- The process relies on turbulent flow within the Venturi tube, leading to rapid mixing and aggregation of lipid particles at the nanoscale, influenced by factors like injection rate and stabilizer concentration.
- The optimum conditions found include an injection rate of 1.6 mL/min and a recirculation rate of 4.2 L/min, resulting in nanoparticles with a size of 212.0 nm, a zeta potential of -19.9 mV, and a high process yield of 96.0%.
