On human tissue kallikrein activity in urine of Brazilian White and Black primary hypertensive patients.

Objective: To evaluate the possible relationship between the human tissue kallikrein amidase activity with sex and ethnicity in Brazilian primary hypertensive patients.

Design: Population-based study.

Participants: One hundred men and women, Black and White primary hypertensive patients aged 20 years and older were selected.

Effect of propafenone on the contractile activity of Latissimus dorsi muscle isolated in an organ chamber: experimental study in rats.

Objective: To study the effect of propafenone on the contractile function of latissimus dorsi muscle isolated from rats in an organ chamber.

Methods: We studied 20 latissimus dorsi muscles of Wistar rats and divided them into 2 groups: group I (n=10), or control group - we studied the feasibility of muscle contractility; group II (n=10), in which the contralateral muscles were grouped - we analyzed the effect of propafenone on muscle contractility. After building a muscle ring, 8 periods of sequential 2-minute baths were performed, with intervals of preprogrammed electrical stimulation using a pacemaker of 50 stimuli/min.