Synthesis, Biological, and Immunological Properties of Cyclic Peptides from Plasmodium Falciparum Merozoite Surface Protein-1.

Effective structural mimics of a functionally important epitope from the malarial Merozoite Surface Protein-1 (MSP-1) include N-backbone cyclic peptides such as 1. They mimic the interaction of MSP-1 with human erythrocytes and can be used to induce parasite-specific monoclonal antibodies.