Publications by authors named "Eduardo F Nakamura"

Article Synopsis
  • Researchers have advanced the understanding of breast cancer diversity but face challenges with the complex PAM50 gene signature due to its high cost and complexity.
  • This study investigates the effectiveness of using smaller gene subsets from the PAM50 gene signature, applying a method called "Few-Shot Genes Selection" to evaluate their classification performance with a Support Vector Machine (SVM) model.
  • Results indicate that certain reduced gene sets, containing only 36 genes, can match or exceed the performance of the full PAM50 signature, suggesting they could lead to more efficient and affordable diagnostic tools in breast cancer research and clinics.
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Breast cancer is the second most common cancer type and is the leading cause of cancer-related deaths worldwide. Since it is a heterogeneous disease, subtyping breast cancer plays an important role in performing a specific treatment. Gene expression data is a viable alternative to be employed on cancer subtype classification, as they represent the state of a cell at the molecular level, but generally has a relatively small number of samples compared to a large number of genes.

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Target tracking is an important application of wireless sensor networks. The networks' ability to locate and track an object is directed linked to the nodes' ability to locate themselves. Consequently, localization systems are essential for target tracking applications.

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Routing is a basic function in wireless sensor networks (WSNs). For these networks, routing algorithms depend on the characteristics of the applications and, consequently, there is no self-contained algorithm suitable for every case. In some scenarios, the network behavior (traffic load) may vary a lot, such as an event-driven application, favoring different algorithms at different instants.

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This work presents a data-centric strategy to meet deadlines in soft real-time applications in wireless sensor networks. This strategy considers three main aspects: (i) The design of real-time application to obtain the minimum deadlines; (ii) An analytic model to estimate the ideal sample size used by data-reduction algorithms; and (iii) Two data-centric stream-based sampling algorithms to perform data reduction whenever necessary. Simulation results show that our data-centric strategies meet deadlines without loosing data representativeness.

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