Publications by authors named "Eduardo Campagnoli"

Article Synopsis
  • This study examined how effective a drug-modified tissue conditioner is for treating denture stomatitis in Wistar rats infected with Candida albicans.
  • Rats wore contaminated devices for 4 days, after which different treatments, including antifungal agents nystatin and chlorhexidine, were added to tissue conditioners, showing a notable reduction in microbial presence.
  • Results indicated that integrating antifungal agents into soft tissue conditioners can significantly improve treatment outcomes for denture stomatitis.
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Background: Various surgical approaches have been employed to manage gingival recession, including subepithelial connective tissue grafting, which has yielded favorable outcomes.

Methods And Results: We present the case of a 17-year-old patient who developed gingival recession on tooth #6 following an esthetic crown lengthening procedure. The recession was treated with a subepithelial connective tissue graft; however, this case details the occurrence of two epithelial cysts adjacent to the region subjected to the surgical procedure, 6 months after surgery.

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This study compared different conditions to establish a rat model of denture stomatitis. Immunocompetent Wistar rats were divided into two groups (n = 35): Tetracycline = administration of 0.83 mg/ml of tetracycline hydrochloride 7 days before induction of denture stomatitis and amoxicillin = administration of 0.

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Bioactive glasses have been recommended for the occlusion of dentinal tubules in treating cervical dentin hypersensitivity. This study evaluates an in vivo model of dentin exposure, and tests the efficacy of bioglass treatments. Thirty male Wistar rats received gingival recession surgery on the upper left first molar.

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Objective: Type 2 diabetes mellitus (T2DM) is a disease of global impact that has led to an increase in comorbidities and mortality in several countries. Immunoexpression of the incretin hormones such as glucagon-like peptide-1 (GLP-1) and peptide YY (3-36) (PYY3-36) can be used as a scorer in the gastrointestinal tract to analyze L-cell activity in response to T2DM treatment. This study aimed to investigate the presence, location, and secretion of L cells in the small intestine of patients undergoing the form of bariatric surgery denominated adaptive gastroenteromentectomy with partial bipartition.

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Background: Croton oil (CO) is used by dermatologists and plastic surgeons in deep chemical peels. It is mixed with phenol, water, and a soap in Baker-Gordon's or Hetter's formulas. There is controversy as to whether CO or phenol is the active agent in the dermal effect of deep chemical peels.

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Objective: To evaluate the influence of light emitted from two Polywave®, LED light-curing units (LCU) on in vivo pulp temperature (PT) rise and signs of acute inflammatory response in pulps of human premolar having deep Class V preparations.

Methods: Sixty intact, first premolars from 15 volunteers requiring extraction received infiltrative anesthesia. A sterile thermocouple probe was inserted within the pulp tissue through a minute occlusal pulp exposure in only 45 teeth (n = 9) to continuously monitor PT (°C).

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Objective: This study evaluated the temperature increase in swine gingival temperature after exposure to light emitted by a Polywave LED light curing unit (LCU, Bluephase 20i, Ivoclar Vivadent).

Methods: After local Ethics Committee approval (protocol 711/2015), 40 pigs were subjected to general anesthesia and the LCU tip was placed 5mm from the buccal gingival tissue (GT) close to lower lateral incisors. A thermocouple probe (Thermes WFI, Physitemp) was inserted into the gingival sulcus before and immediately after exposure to light.

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Article Synopsis
  • Euphorbia umbellata, commonly known as leitosinha, is traditionally used in southern Brazil for gastric issues and offers analgesic and anti-inflammatory benefits.
  • A study examined the anti-ulcer effects of a methanolic bark fraction (MF), assessing its activity both in lab settings (in vitro) and with live subjects (in vivo), focusing on antioxidant and antibacterial properties.
  • Results indicated that MF effectively reduced ulcers in animal models, exhibited strong antioxidant properties, and showed potential mechanisms like prostaglandin pathways and glutathione involvement, supporting its traditional use in folk medicine.
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The nasolabial cyst or Klestadt cyst is a relatively uncommon nonodontogenic cyst that develops in the nasal alar region; it has uncertain pathogenesis. This lesion has slow growth and variable dimensions and is characterized clinically by a floating tumefaction in the nasolabial fold area around the bridge of the nose, causing an elevation of the upper lip and relative facial asymmetry. Diagnosis is primarily made clinically; if necessary, this is complemented by imaging.

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Objectives: The aim of this study was to verify the impact of dentofacial deformity on quality of life and explore gender and age differences.

Material And Methods: The impact of dentofacial deformity (DD) on quality of life was evaluated through questionnaires; Short Form Health Survey (SF36), Oral Health Impact Profile Questionnaire (OHIP), Orthognathic Quality of Life Questionnaire (OQLQ) and a single question answered by a Visual Analogue Scale.

Results: Significant differences between male and female patients were observed in domains of OQLQ (oral function, P = 0.

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Background: The study of MMPs' behavior in carious lesions contributes to the understanding of the mechanisms involved in dentin reorganization after restoration.

Aim: To compare the abundance and localization of MMPs 2, 8, and 9 in infected dentin before and after restoration.

Design: The sample consisted of 23 young permanent molars with active deep carious lesions.

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Purpose: The objective of this article is to describe a method to construct an intraoral acrylic device that permits a reline material to be added to the inner surface of the palatal plate.

Materials And Methods: Fifteen 60-day-old adult female rats (Rattus Norvegicus Albinus Wistar), weighing 150 to 250 g were used for this study and allocated to three groups (n = 5): G1, animals wearing a heat-polymerized acrylic resin palatal plate (Lucitone 550) for 14 days; G2, animals wearing a heat-polymerized acrylic resin palatal plate (Lucitone 550) relined with Tokuyama Rebase II for 14 days; and G3, animals maintained under the same conditions as the experimental groups, without wearing palatal plates for 14 days. The manipulation of the animals followed the guidelines of the Brazilian College of Animal Experimentation, under the approval of the animal ethics committee of the State University of Ponta Grossa.

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Aim: To assess the histopathological changes of rat palatal mucosa exposed to soft reline materials.

Methods: Forty-five adult female Wistar rats with controlled living conditions and fed ad libitum were employed. Palatal appliances of heat-polymerized acrylic resin Lucitone 550 were manufactured and worn by forty animals during 14 days.

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Malva sylvestris L. is widely used in medicine for treatment of inflammatory processes. The plant has anti-inflammatory properties due to substances such as mucilage, flavonoids, and tannins.

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Article Synopsis
  • Synadenium grantii, a plant used in southern Brazil for treating neoplastic diseases, was studied for its antitumoural properties against the B16F10 melanoma cell line using both in vitro and in vivo methods.
  • The latex from the plant showed diminishing cell viability in a time and concentration-dependent manner, leading to a significant 40% tumor volume reduction in mice.
  • Phytochemical analysis identified compounds like euphol and citrostadienol, with the latter demonstrating limited cytotoxic effects, while the latex itself was found to have notable cytotoxic activity against melanoma cells.
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Purpose: This study was conducted to investigate the morphological effects of the absence of estrogen on alveolar wound healing of young female rats after tooth extraction.

Materials And Methods: A total of 60 4- to 6-week-old female rats underwent bilateral ovariectomy (OVX) or sham operations. Three weeks later, the first mandibular molars were extracted.

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Rhinoliths are calcified masses formed within the nasal cavity because of the solidification of mucus, debris, or foreign objects by gradual accretion of mineral salts. They are mostly asymptomatic and incidentally diagnosed, although some patients may complain of nasal discharge and obstruction. Ulceration of the nasal mucosa, facial swelling, and bone destruction are less frequently observed but bring about difficulties for differential diagnoses with several pathologic entities.

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Plasma cell neoplasia is a lymphoid neoplastic proliferation of B cells. This denomination encloses multiple myeloma (MM), solitary bone plasmacytoma and extramedullary plasmacytoma. MM consists of a clonal proliferation of plasma cells based in the bone marrow, with various degrees of differentiation.

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A double lip is an anomaly that may be either congenital or acquired. It occurs most often in the upper lip, although both upper and lower lips are occasionally involved. Surgical intervention (simple excision) produces good functional and cosmetic results.

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