Publications by authors named "Eduardo Borsini"

 The clinical manifestations of obstructive sleep apnea (OSA) are different between genders. Though there are several screening questionnaires for OSA, their performance in females is not fully understood, as women have been historically underrepresented in research studies.  To assess the performance of screening questionnaires and their capacity to identify a moderate to severe apnea-hypopnea index (AHI) in women.

View Article and Find Full Text PDF

Purpose: To develop equations to predict therapeutic continuous positive airway pressure (CPAP) based on home-based CPAP titration, including the type of interface used.

Method: Retrospective study conducted in adult patients with obstructive sleep apnea (OSA) who used home-based autoCPAP titration (AutoSet S10, ResMed). CPAP was obtained manually through a visual analysis of autoCPAP data (CPAP) and automatically using the 95th percentile pressure (CPAP).

View Article and Find Full Text PDF

 Many patients abandon CPAP treatment because they find the mask uncomfortable. Therefore, specialists may benefit from the predictive value of airway assessment tools.  To identify nasal ventilation failure through the Nasal Obstruction Symptom Evaluation (NOSE) scale in patients with obstructive sleep apnea (OSA) who undergo home-based auto-adjusting CPAP titration and to determine whether there is a correlation between NOSE score and the type of mask selected.

View Article and Find Full Text PDF

 Obstructive sleep apnea (OSA) is a disorder characterized by recurrent pharyngeal obstruction during sleep, in which upper airway anatomy plays a key role in its pathogenesis. The aim of this study was to describe whether the quantification of cervical fat tissue volume (CFTV) obtained by Computed Tomography (CT)cephalometry is related to the severity of OSA.  Retrospective study between 2018 and 2020 in those patients > 18 years old, with diagnosis of OSA who performed a volumetric cephalometric imaging.

View Article and Find Full Text PDF

Introduction: CPAP therapy is the first line treatment for sleep apnea and its effectiveness depends on adherence. Face to face control and follow-up was limited due to the fact that our country was immersed in social isolation due to the COVID-19 pandemic as of March 2020. In order to assess whether CPAP adherence was maintained in patients with obstructive sleep apnea (OSA), in two hospitals during the COVID-19 pandemic and compare it with the pre-pandemic situation on a historical control basis in the city of Buenos Aires.

View Article and Find Full Text PDF

Introduction: Home mechanical ventilation in chronic respiratory failure improves quality of life and decreases hospitalizations. In order to know clinical characteristics, resource consumption and survival, we proposed an analysis of the vital trajectory during six years.

Methods: Descriptive and retrospective study.

View Article and Find Full Text PDF

Purpose: The aims of this study were to assess the cut-off values for oxygen desaturation index ≥ 3% (ODI3) to confirm obstructive sleep apnea (OSA) in subjects undergoing polysomnography (PSG) and home-based respiratory polygraphy (RP), and to propose an algorithm based on pulse oximetry (PO) for initial management of patients with suspected OSA.

Methods: This was an observational, cross-sectional, retrospective study. ODI3 was used to classify subjects as healthy (no OSA = AHI < 5 or < 15 events/h) or unhealthy (OSA = AHI ≥ 5 or ≥ 15 events/h).

View Article and Find Full Text PDF

Purpose: To assess the relationship between hypoxemia during polysomnography (PSG) and patient-reported night sweats (NS).

Methods: This retrospective observational study included adult patients who completed a standardized sleep questionnaire and the Epworth Sleepiness Scale (ESS) before PSG.

Results: We included 1397 patients (41% women).

View Article and Find Full Text PDF

Introduction: To assess CPAP acquirement, compliance, and dropout rates among OSA patients three years after the prescription.

Material And Methods: We assessed CPAP acquirement (Acq), compliance (Comp), and dropout (Dout) through a telephone survey. We interviewed 156 patients; ESS: 9.

View Article and Find Full Text PDF

Introduccion: Intermittent chronic hypoxia produced during obstructive sleep apneas (OSA) leads to oxidative stress, and consequently to a state of systemic inflammation. There are no biomarkers that assess the degree of inflammation and are related to the severity of this disease. The red cell distribution amplitude and the ultrasensitive reactive C protein are sensitive to the systemic inflammation generated by oxidative stress.

View Article and Find Full Text PDF

Objective: To compare pulse oximetry with manual analysis against all signals of respiratory polygraphy.

Material And Methods: This retrospective study estimated sensitivity (S), specificity (Sp) and positive/negative likelihood ratio (LR+/-) of the oxygen desaturation index (ODI-test) and apnea-hypopnea index (AHI-reference).

Results: 3854 patients (61.

View Article and Find Full Text PDF

The main aim of this international consensus document on obstructive sleep apnea is to provide guidelines based on a critical analysis of the latest literature to help health professionals make the best decisions in the care of adult patients with this disease. The expert working group was formed primarily of 17 scientific societies and 56 specialists from a wide geographical area (including the participation of 4 international societies), an expert in methodology, and a documentalist from the Iberoamerican Cochrane Center. The document consists of a main section containing the most significant innovations and a series of online manuscripts that report the systematic literature searches performed for each section of the international consensus document.

View Article and Find Full Text PDF

Obstructive sleep apnea (OSA) is a prevalent condition. OSA is defined as very severe when the apneas/ hypopneas index (AHI) is greater than 60 events/hour. However, its prevalence remains uncertain.

View Article and Find Full Text PDF

Polysomnography without real-time technical supervision (sleep test level II) h as been described with adequate quality of neurological and respiratory signals. We compare the efficiency and quality of sleep in hospitalized patients and in the sleep laboratory. The study was retrospective, in a consecutive sample of systematic collection based on PSG level II.

View Article and Find Full Text PDF

Objective: to compare mountaineers with and without asymptomatic sleep apnea (OSA) before the ascent and to study high altitude-related sleep disorders, its interaction with metabolic, neuroendocrine and immunological components.

Material And Methods: During an expedition to Mount Aconcagua, researchers assessed the respiratory polygraphy (RP), clinical condition and inflammatory parameters, and rhythm of cortisol secretion in mountaineers sleeping at different altitude camps.

Results: 8 athletes (4 women), 36 years old (25-51) participated.

View Article and Find Full Text PDF

Objective: To compare the performance of Epworth Sleepiness Scale (ESS) and tiredness symptom with the apnea-hypopnea index (AHI) in a population referred to home sleep tests.

Materials And Methods: This correlational study assessed adult patients through questionnaires and respiratory polygraphy (RP). We estimated sensitivity (S), specificity (Sp), predictive values (PV), odds ratio (OR) adjusted multivariate model and area under ROC curve for each sex and severity.

View Article and Find Full Text PDF

Background And Objective: The usefulness of pulse oximetry for the management of obstructive sleep apnea is controversial. The aim of this study was to assess the accuracy for indication of Continuous Positive Airway Pressure (CPAP) treatment in patients with suspected obstructive sleep apnea (OSA) based on clinical and oximetry data as compared to polysomnography (PSG).

Methods: This multicenter observational study involved seven sleep laboratories.

View Article and Find Full Text PDF

Background: The prevalence of obstructive sleep apnea (OSA) increases with age. However, older adults have limited perception of the symptoms related with poor sleep quality.

Objectives: To know the frequency and characteristics of age-related OSA in a large population with clinical suspicion of sleep apnea.

View Article and Find Full Text PDF

Objective: To evaluate the performance of clinical criteria (CC) for diagnosis and initiation of empirical treatment with continuous positive airway pressure (CPAP) in patients with suspected obstructive sleep apnea (OSA) compared with the treatment decision based on sleep studies (polysomnography or respiratory polygraphy), guidelines, and experience of participating physicians.

Methods: This was a simulated intention-to-treat study in a retrospective (G1) and prospective (G2) cohort. Four observers (two per group) called CC1 and CC2 reviewed the sleep questionnaires and indicated CPAP if the patients presented snoring, frequent apneas (≥ 3-4/week), body mass index (BMI) > 25 kg/m, sleepiness (Epworth > 11), or tiredness (at least 3-4 times per week) and some comorbidity (hypertension, coronary/cerebrovascular event, diabetes).

View Article and Find Full Text PDF

Objectives: To compare interfaces performance during home-based automatic titration (APAP).

Methods: Retrospective study based on APAP titration from Obstructive Sleep Apnea Syndrome (OSA) patients.

Results: 707 patients, 513 men (70.

View Article and Find Full Text PDF

Objectives: To evaluate patient's satisfaction, efficacy and adherence to CPAP with a hybrid nasal mask (DW) we tested patients with OSA in unattended setting under real-life conditions.

Material And Methods: Prospective, comparative study using DW mask 7 days against habitual mask in patients adapted to CPAP therapy.

Results: We analyzed 52 patients: 35 men (67%) with IAH mean; 24.

View Article and Find Full Text PDF

Home mechanical ventilation represents a standard of care in the insufficiency of the ventilatory pump. The follow-up model could change the hospitalization rate. In order to study hospitalizations in patients with home mechanical ventilation, a descriptive study was designed on a systematic collection database.

View Article and Find Full Text PDF

: Hypertension (HT) and obstructive sleep apnea-hypopnea syndrome (OSA) are prevalent and frequently related pathologies. The predictive value of screening questionnaires in cardiovascular settings is not totally clear and could be useful to select candidates for the sleep test. : We performed a prospective study in adults with suspected HT referred to a day-care hospital.

View Article and Find Full Text PDF