Implementation of an Enzyme Membrane Reactor to Intensify the α--Glycosylation of Resveratrol Using Cyclodextrins.

The -glycosylation of resveratrol increases both its solubility in water and its bioavailability while preventing its oxidation, allowing a more efficient use of this molecule as a bioactive ingredient in pharmaceutical and cosmetic applications. Resveratrol -glycosides can be obtained by enzymatic reactions. Recent developments have made it possible to selectively obtain resveratrol α-glycosides from the β-cyclodextrin-resveratrol complex in water with a yield of 35%.

[Intraductal papillary mucinous neoplasm and recurrent pancreatitis].

Ohashi described for the first time the IPMN on 1982 as a pancreatic neoplasia with mucine cells forming papillae and producing dilatation of the main pancreatic duct or its branches. The IPMN represent the 1% of the pancreatic tumors and 5% of the cystic neoplasias. It is potentially malignant in a period of five years being more frequent in males between 60-70 and clinically these patients' presents as acute, recurrent or chronic pancreatitis, with an incidence of malignancy from 25% to 70%.

[New Beta-lactam agent in the treatment of intra-abdominal sepsis: double blind and randomized stage III study of ertapenem versus piperacillin/tazobactam].

The clinical and safety efficacy of a new wide spectrum beta-lactam agent for most pathogen intra-abdominal infection germs is evaluated herein. Its chemical name is Ertapenem (MK-0826). Its pharmacokinetic characteristics and the known antibacterial spectrum enable the potential use of one daily dose in the treatment of infections by aerobic and anaerobic bacteria.

[COLON AND RECTUM CANCER SURGERY].

In the last few years, an enormous progress has been achieved in the treatment of Colorectal Cancer due to a better know ledge of the biology, natural history, prevention and treatment of colon and rectum adenocarcinoma. Genetic alterations produce changes in thecolonic mucosa that lead to the formation of adenoma and eventually, its transformation into cancer. At present, it is well established that the Adenomatous Polyp preceeds Colorectal Cancer.