Publications by Eduardo Augusto Rosa

Publications by authors named "Eduardo Augusto Rosa"

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Oral lichen planus and malignant transformation: The role of p16, Ki-67, Bub-3 and SOX4 in assessing precancerous potential.

Eduardo Augusto Rosa Aura Maria Hurtado-Puerto Denise Pinheiro Falcão Aline Patricia Brietzke Luiz Eduardo De Almeida Prado Franceschi

Exp Ther Med

May 2018

Article Synopsis

The study investigates the risk of malignant transformation in oral lichen planus (OLP) by analyzing the expression levels of potential precancerous biomarkers: p16, Ki-67, Bub-3, and SOX4.
Significant differences were found in p16 and Ki-67 positivity indices among OLP, oral dysplasia, and other conditions, indicating varying levels of malignancy risk.
The findings point to the need for monitoring specific OLP lesions due to their intermediate malignant potential, especially highlighting the different behavior of SOX4 in oral dysplasia compared to OLP.

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In situ carcinoma developed over oral lichen planus: a case report with analysis of BUB3, p16, p53, Ki67 and SOX4 expression.

Eduardo Augusto Rosa Erica Negrini Lia Sergio Bruzadelli Macedo Rivadavio Fernandes Batista de Amorim

J Appl Oral Sci

March 2016

Oral lichen planus (OLP) represents a common mucocutaneous disease. Various authors have suggested that OLP has malignant potential; however, the mechanisms involved in malignant transformation have not yet been elucidated. A 79-year-old man presented a white lesion for five months in the buccal mucosa diagnosed as OLP.

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