Publications by authors named "Eduardo A Almeida"

Acute hypoxia is known to increase the generation of reactive oxygen species (ROS), leading to modulation in antioxidant defenses. Pollutant exposure can potentiate ROS generation during hypoxic events and impair antioxidant defenses, increasing the susceptibility of hypoxia-tolerant fishes, such as the Nile tilapia (Oreochromis niloticus), to oxidative stress. The purpose of this study was to evaluate oxidative stress responses of O.

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Bees are essential pollinators for wild, ornamental, and agricultural plants, but human activities have disrupted their habitats, threatening their persistence. Although bees face numerous challenges in habitats heavily modified by human activities, certain species persist and thrive there. This review synthesizes recent literature on two types of traits that help bees survive in human-modified environments: preadaptive traits, which evolved before these environments existed, and adaptive traits, which have evolved in response to new conditions.

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  • Pesticides from rice farming can harm non-target organisms, impacting biodiversity, leading researchers to study their presence in river water and their effects on Boana faber tadpoles.
  • The study found no major developmental issues in tadpoles but noted increased malondialdehyde (MDA) levels indicating oxidative stress after pesticide exposure, particularly with herbicide BTZ and fungicide TBZ.
  • Histological examinations revealed significant changes in the tadpoles, such as inflammation and liver enzyme activity alterations, highlighting the negative impact of rice pesticides on local aquatic ecosystems and biodiversity.
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Pesticides are released into the environment daily, and their effects on nontarget species in aquatic ecosystems have been widely reported. To evaluate the adverse effects caused in adults of Danio rerio species exposed to the pesticides abamectin, difenoconazole, and their commercial formulations (Kraft 36EC® and Score 250EC®), both isolated and in mixtures, biochemical biomarkers were analyzed in the gills of organisms exposed to sublethal concentrations. To this end, the activities of the enzymes 7-ethoxyresorufin-O-deethylase (EROD), glucuronosyltransferase (UDPGT), glutathione-S-transferase (GST), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), lipid hydroperoxide (LH), and malondialdehyde (MDA), which are indicative of oxidative stress, were measured after 48 h of exposure to the different pesticide treatments.

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Coastal environments, such as those in the Santa Catarina State (SC, Brazil), are considered the primary receptors of anthropogenic pollutants. In this study, our objective was to evaluate the levels of emerging contaminants (ECs) and persistent organic pollutants (POPs) in indigenous Crassostrea gasar oysters from different regions of SC coast in the summer season (March 2022). Field collections were conducted in the São Francisco do Sul, Itajaí, Florianópolis and Laguna coastal zones.

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Synthetic glucocorticoids are often found in surface waters and can cause harmful effects to aquatic organisms such as amphibians. In this work we evaluated the effects of the drugs prednisone (PD) and prednisolone (PL) on developmental, molecular, blood, biochemical and histological markers. Aquarana catesbeianus tadpoles were exposed for 16 days to environmentally relevant concentrations of 0, 0.

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This study aimed to carry out a general diagnosis of the contamination of the coastal marine environment of the Santa Catarina state (SC, Brazil) by different classes of environmental pollutants, as well as to evaluate possible adverse effects of the contaminants on biochemical biomarkers of oysters, Crassostrea gasar and Crassostrea rhizophorae. 107 chemicals were evaluated in water, sediment and oyster samples from nine sites along the coastline of SC. We also examined various biochemical biomarkers in the oysters' gills and digestive glands to assess potential effects of contaminants.

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This study aimed to assess the combined effect of hypoxia and exposure to diesel on biochemical parameters of Perna perna mussels. Mussels previously kept for 48 h in clean seawater were submitted to hypoxia for 24 h followed by reoxygenation in clean seawater for 48 h. The same procedure was done but using seawater containing 0.

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Rampant urbanization in coastal environments turns areas close to the seafront into a highly impacted ecosystem, possibly affecting the health and well-being of resident animal species. The tuco-tuco Ctenomys flamarioni is an endemic and endangered subterranean mammal from southern Brazil, and the anthropic influence was considered one of the main threats to the species. In this context, the present study aimed to investigate the patterns of oxidative status of the species in natural areas with different levels of anthropogenic disturbance.

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  • The study investigated how temperature (25 and 32 °C) influences the response of bullfrog tadpoles to different concentrations of the atrazine metabolite 2-hydroxyatrazine (2-HA) over 16 days.
  • The results showed that 2-HA reduced the activity of the enzyme superoxide dismutase (SOD) at 25 °C and caused liver and kidney damage, particularly affected by higher temperatures.
  • Overall, the findings suggest that environmentally relevant levels of 2-HA can impact biomarker responses and organ morphology in tadpoles, with temperature playing a significant role in these alterations.
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  • - The study investigated how ergothioneine (ERT) affects red blood cell adaptation by analyzing gene expression in specific signaling pathways during erythroid differentiation and oxidative stress using K562 cells.
  • - Two concentrations of ERT (1 nM and 100 µM) were tested with and without oxidative stress, revealing that lower concentration ERT significantly enhanced several protective gene expressions at different stages of cell differentiation.
  • - The findings suggest that ERT has a cytoprotective role mainly through the Nrf2-ARE pathway and potentially aids in red blood cell proliferation and differentiation via the FoxO3 pathway.
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  • * The study analyzed how MEL affects specific signaling pathways in K562 erythroleukemic cells when subjected to OS induced by hydrogen peroxide, by evaluating cell viability and gene expression.
  • * Results showed that MEL can restore Nrf2 levels and that different concentrations of MEL had distinct impacts on gene expression related to antioxidants and apoptosis, highlighting its potential as a therapeutic approach for diseases linked to oxidative stress.
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Global demand for crops will continue increasing over the next few decades to cover both food and biofuel needs. This demand will put further pressure to expand arable land and replace natural habitats. However, we are only beginning to understand the combined effects of agrochemicals and land-use change on tropical freshwater biodiversity.

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γ-aminobutyric acid (GABA) is one of the main neurotransmitters involved in the adaptation processes against the damage that hypoxia can cause to the brain. Due to its antagonist action on GABA receptors, the insecticide fipronil can turn the fish more susceptible to the negative effects of hypoxia. This study aimed to understand better if fipronil affects these GABAergic responses of Tilapia ahead to hypoxia.

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  • Disturbance in stream surroundings affects water quality and harms aquatic life, prompting a study on the impact of land use on fish biomarkers in Brazilian savanna streams.
  • The study focused on the Neotropical tetra fish, Astyanax lacustris, with fish exposed in cages across 13 streams during both dry and wet seasons, analyzing blood, liver, and gills for various biomarkers.
  • Findings revealed that increased anthropogenic disturbance correlated with genetic damage and reduced liver enzyme activity while also indicating negative impacts on water quality, suggesting that multibiomarker strategies can effectively assess the effects of landscape changes.
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The influence of temperature (25 and 32 °C) on the negative effects of the herbicide tebuthiuron (TBU, 0, 10, 50 and 200 ng.L-1, 16 days) on thyroid function and metamorphosis of Lithobates catesbeianus tadpoles was evaluated. Metamorphosis was accelerated by TBU exposure at 25 ºC, but delayed at 32 ºC with considerable losses of body mass.

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Introduction: Schizophrenia is a complex psychiatric disorder that affects approximately twenty million people worldwide. Various factors have been associated with the physiopathology of this disease such as oxidative stress, which is an imbalance between pro-oxidant and antioxidant molecules.

Objective: This study evaluated the association between biomarkers of oxidative stress and response to pharmacological treatment among patients with schizophrenia in the context of their clinical information, demographic data, and lifestyle.

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Cocaine (COC) is a powerful illicit drug frequently detected in the aquatic environment. COC acts by inhibiting the reuptake of dopamine (DOPA) and 5-hydroxytryptamine (5-HT - serotonin) and causes endocrine disturbances in mammals. This study investigated similar effects from cocaine exposure in the marine mussel Perna perna, as well as neurotoxicity and energy imbalances.

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  • Tebuthiuron (TBU) is a widely used herbicide in sugarcane fields that poses risks to aquatic life, particularly bullfrog tadpoles, due to its slow degradation and water solubility.
  • The study examined how varying temperatures (25 and 32 °C) affected the harmful impacts of TBU on bullfrog tadpoles, with increases in TBU concentration (0, 10, 50, and 200 ng/L) leading to significant changes in enzyme and gene activity related to metabolism and antioxidant defense.
  • The findings revealed that both TBU exposure and elevated temperature disrupted the tadpoles' metabolic balance, resulting in altered biomarker responses and liver damage, specifically at higher TBU concentrations
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Imbalance of sexual steroids milieu and oxidative stress are often observed during aging and correlated to prostate disorders. Likewise, high-fat intake has been related to prostate damage and tumor development. Melatonin (MLT) is an antioxidant whose secretion decreases in elderly and is also suggested to protect the gland.

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In tropical climate countries, animal production faces a huge challenge, being the high solar irradiation levels an important factor that negatively influences the welfare and animal performance. The purpose of this research was to check the environment inside mobile shelters with different kinds of cover materials. This research has been developed at the State University of Goiás, Brazil, being used four different cover materials: DFPC, double-faced plastic canvas; PVC, polyvinyl chloride; VFB, tiles made with vegetable fiber and bitumen; and VFBW, tiles made with vegetable fiber and bitumen being the outer face painted white.

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The increasing demand for biofuels favored the expansion of sugarcane and, as a consequence, in the consumption of pesticides in Brazil. Amphibians are subject to pesticide exposure for occurring in or around sugarcane fields, and for breeding at the onset of the rainy season when pesticide consumption is common. We tested the hypothesis that herbicides used in sugarcane crops, although employed for weed control and manipulated at doses recommended by the manufacturers, can cause lethal and sublethal effects on amphibian larvae.

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Lubricant oils are among oil-based products that are not fully consumed during its use, thereby producing non-biodegradable residues which can cause contamination of natural systems. This study evaluated the toxicity of new and used lubricating oil (0.01 and 0.

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