Publications by authors named "Eduard Nitschke"
Article Synopsis
- The study investigates how interferon (IFN) signaling pathways affect autoantibody production and symptoms in primary Sjögren's syndrome (pSS), aiming to improve diagnostics and personalized treatments.
- Researchers analyzed samples from 34 pSS patients and 38 healthy donors, finding elevated IFN pathway molecules like STAT1, STAT2, and IRF9 in most T and B cells from patients, indicating heightened signaling activity.
- Results suggest that high levels of STAT1 and IRF9 are linked to specific autoimmune features and can serve as biomarkers for disease severity and the presence of extraglandular symptoms in pSS patients.
