Epidemiology, antibiotic therapy and clinical outcomes of healthcare-associated pneumonia in critically ill patients: a Spanish cohort study.

Purpose: Information about healthcare-associated pneumonia (HCAP) in critically ill patients is scarce.

Methods: This prospective study compared clinical presentation, outcomes, microbial etiology, and treatment of HCAP, community-acquired pneumonia (CAP), and immunocompromised patients (ICP) with severe pneumonia admitted to 34 Spanish ICUs.

Results: A total of 726 patients with pneumonia (449 CAP, 133 HCAP, and 144 ICP) were recruited during 1 year from April 2011.

Discrepancy between clinical criteria for diagnosing acute respiratory distress syndrome secondary to community acquired pneumonia with autopsy findings of diffuse alveolar damage.

Diffuse alveolar damage (DAD) is the underlying pathological finding in most cases of acute respiratory distress syndrome (ARDS). The objective of this study was to compare clinical criteria for ARDS secondary to community acquired pneumonia with autopsy findings of DAD and to determine the discrepancy rate between the two. We compared prospectively obtained clinical diagnosis of ARDS secondary to community acquired pneumonia with autopsy findings of DAD and pneumonia.

[Serious postoperative complications after esophagectomy for esophageal carcinoma: analysis of risk factors].

Introduction: To identify risk factors for postoperative morbidity and mortality in patients undergoing esophagectomy for esophageal cancer.

Design And Patients: The population comprised 159 patients with locally advanced esophageal cancer, undergoing esophagectomy between January 1985 and December 2004.

Results: Infections were the main cause of both complications and postoperative mortality.

Risk factors and prognosis of catheter-related bloodstream infection in critically ill patients: a multicenter study.

Objective: To assess the risk factors associated with CR-BSI development in critically ill patients with non-tunneled, non-cuffed central venous catheters (CVC) and the prognosis of the episodes of CR-BSI. Design and setting; prospective, observational, multicenter study in nine Spanish Hospitals.

Patients: All subjects admitted to the participating ICUs from October 2004 to June 2005 with a CVC.

A 7-year study of severe hospital-acquired pneumonia requiring ICU admission.

Objective: To examine the characteristics, prognostic factors, and outcome of patients with severe hospital-acquired pneumonia admitted to the ICU.

Design And Setting: Prospective observational clinical study in two medical-surgical ICUs with 16 and 20 beds

Patients And Participants: During a 7-year period all hospitalized patients requiring admission to either ICU for hospital-acquired pneumonia were followed up.

Measurements And Results: We diagnosed 96 episodes of severe hospital-acquired pneumonia, and in 67 cases a causal diagnosis was made.