Publications by authors named "Edson Luiz Tarsia Duarte"
What else in times of COVID-19? The role of minimally invasive autopsy for the differential diagnosis of acute respiratory failure in a case of kala-azar.
Rev Inst Med Trop Sao Paulo
June 2023
Article Synopsis
- - Visceral leishmaniasis (VL) is a serious disease spread by parasites, mainly affecting poorer regions, with 50,000-90,000 cases reported globally each year, especially prevalent in Brazil.
- - The disease can lead to severe symptoms like fever and organ enlargement, and if untreated, it can have a mortality rate of up to 90%, primarily due to infections and organ failure.
- - A case study highlights a 25-year-old Brazilian woman who, after traveling to rural areas, was hospitalized for COVID-19 and later diagnosed post-mortem with VL, pneumonia, and a bloodstream infection, emphasizing the disease's severe impact.
Article Synopsis
- - This study explores the relationship between multidrug-resistant bacteria and their virulence traits using zebrafish as a model, analyzing 46 strains from Brazilian hospitals that were resistant to colistin and contained specific resistance genes (bla).
- - Ten different sequence types (STs) were identified, with the majority falling under CC258, and certain virulence factors like fimbriae and efflux-pumps were frequently present; however, only ST16 strains showed a significant increase in mortality in zebrafish embryos (52% vs. 29%).
- - The findings suggest that while several virulence factors exist, ST16 is uniquely linked to heightened virulence in the zebrafish model, indicating the need for additional studies to better
In this study, we describe a case report of gonococcal arthritis in a Systemic Lupus Erythematosus patient. Although several mechanisms favor disseminated gonococcal infection (DGI) in patients immunosuppressed by SLE, this association is rarely reported in literature. We performed whole genome sequencing (WGS) of the etiologic agent involved and molecular analysis using a global collection of Neisseria gonorrhoeae strains.
View Article and Find Full Text PDFCarbapenem-resistant colonization and infection is associated with lower overall survival in a cohort of haematopoietic stem-cell transplantation patients: mechanism of resistance and virulence by whole-genome sequencing.
J Med Microbiol
October 2021
Carbapenem-resistant (CRK) infections are a growing concern in immunocompromised patients. The aim of the present study was to evaluate the impact of CRK colonization and infection in overall mortality for haematopoietic stem-cell transplant (HSCT) patients. We also aimed to investigate resistance and virulence profiles of CRK isolates and assess their epidemiological and genetic relatedness.
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