Publications by authors named "Edrick F Villalobos"
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Synopsis of recent research by authors named "Edrick F Villalobos"
- Edrick F. Villalobos's recent research focuses on the roles of p21-activated kinase (PAK) in promoting cell survival and proliferation, particularly in vestibular schwannoma (VS) and meningioma tumors linked to the loss of the NF2 gene product merlin
- The study posits that pharmacological inhibition of PAK can trigger cell death in VS and meningiomas, suggesting a potential therapeutic pathway for treating these tumors
- Utilizing novel small molecule PAK inhibitors, such as PI-8 and PI-15, the research demonstrates their efficacy in disrupting molecular signaling and inducing cell death in affected tumor cells
