Publications by authors named "Edom Woldetsadik"

Purpose: Management of locally advanced rectal cancer (LARC) includes neoadjuvant chemoradiotherapy (NACRT) followed by total mesorectal excision. Recently, total neoadjuvant treatment (TNT) has gained attention. In developing countries, patients with rectal cancer often present at advanced stages.

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Background: The Cancer Survival in Africa, Asia, and South America project (SURVCAN-3) of the International Agency for Research on Cancer aims to fill gaps in the availability of population-level cancer survival estimates from countries in these regions. Here, we analysed survival for 18 cancers using data from member registries of the African Cancer Registry Network across 11 countries in sub-Saharan Africa.

Methods: We included data on patients diagnosed with 18 cancer types between Jan 1, 2005, and Dec 31, 2014, from 13 population-based cancer registries in Cotonou (Benin), Abidjan (CÔte d'Ivoire), Addis Ababa (Ethiopia), Eldoret and Nairobi (Kenya), Bamako (Mali), Mauritius, Namibia, Seychelles, Eastern Cape (South Africa), Kampala (Uganda), and Bulawayo and Harare (Zimbabwe).

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Background: The development of health concepts beyond traditional markers of illness and death has made the evaluation of quality of life (QoL) crucial to patient care. Yet, there is little research evaluating the pre- and post-treatment QoL of cervical cancer survivors in Ethiopia.

Objective: This study aimed to assess the pre- and post-treatment QoL of women diagnosed with advanced-stage cervical cancer.

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Background: Cervical cancer is one of the leading causes of cancer death in women, even though it is a preventable disease. Most deaths occur in low- and middle-income countries. In addition to early detection and receipt of standard treatments, survivorship is an important component of high quality of care across the cancer continuum.

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Article Synopsis
  • The purpose of the document is to provide guidance on vaccinating adults with solid tumors or blood cancers, focusing on their specific needs regarding immunization.
  • A systematic review was conducted, analyzing studies and trials between 2013 and 2023, resulting in 102 publications, mainly centered on the efficacy of COVID-19 vaccines.
  • Key recommendations emphasize the importance of maintaining vaccination status, coordinating among healthcare providers, providing vaccines promptly, and adjusting vaccination plans based on patients' immune status and cancer treatments.
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Purpose: Head and neck cancers (HNCs) are the third most commonly treated cancer with radiation in Ethiopia. Most patients present with advanced stage and are not candidates for curative treatment. The objective of our study is to assess the outcome of hypofractionated palliative radiotherapy (RT) for advanced HNCs in a resource-limited setting.

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Article Synopsis
  • The prognosis for cervical cancer in East Africa shows a wide range of survival rates influenced by public awareness, access to cancer services, and treatment options.
  • A systematic review included 13 studies from several East African countries, focusing on overall survival rates at different time points, which ranged from 26% to 92% over five years.
  • Key factors impacting survival included HIV status, the stage at which patients present, treatment methods, older age, and other health conditions, with one-year and two-year survival rates pooled at 84% and 71%, respectively.
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