Publications by authors named "Edoardo Tringali"
Article Synopsis
- Hypertension and chronic kidney disease (CKD) are interconnected, with high blood pressure worsening kidney health and vice versa, creating a cycle of deteriorating health.
- Managing hypertension in CKD patients is critical as it not only helps preserve kidney function but also reduces cardiovascular risks, which are the leading causes of death in these individuals.
- New treatment options are emerging for CKD that specifically target the interactions between hypertension and kidney disease, potentially transforming how high blood pressure is managed in these patients.
IgA Nephropathy (IgAN) is the most prevalent glomerular disease worldwide. Complement system activation is crucial in its pathogenesis. Few studies correlated serum C3 and C4 with disease activity and prognosis.
View Article and Find Full Text PDFNephrology is an ever-evolving field of medicine. The importance of such a discipline is related to the high clinical impact of kidney disease. In fact, abnormalities of kidney function and/or structure are common in the general population, reaching an overall prevalence of about 10%.
View Article and Find Full Text PDFRationale & Objective: Fabry disease (FD) is an X-linked genetic disorder that causes lysosomal storage of glycosphingolipids, primarily globotriaosylceramide (Gb3) and its derivative globotriaosylsphingosine (lyso-Gb3), with multiorgan dysfunction including chronic kidney disease. Affected individuals may be carriers of gene variants that are of uncertain significance (GVUS). We describe kidney pathology at the early stages of FD-related kidney disease to gain insights into its association with GVUS and sex.
View Article and Find Full Text PDFIntroduction: High-flux hemodialysis membranes may modulate the cytokine storm of SARS-CoV-2, but their impact on chronic hemodialysis (CHD) patients is unknown. The aim of the study was the evaluation of asymmetric cellulose triacetate (ATA) and polymethylmethacrylate (PMMA) dialyzers on inflammatory markers and clinical outcomes in CHD patients with SARS-CoV-2.
Methods: A prospective, observational study on CHD patients with SARS-CoV-2 was carried out.