Publications by authors named "Edmundo Hofmann"

(1) Background: Gastric cancer, the fourth most common cause of death from tumors in the world, is closely associated with . Timely diagnosis, therefore, is essential to achieve a higher survival rate. In Chile, deaths from gastric cancer are high, mainly due to late diagnosis.

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is the main bacteria associated with gastroduodenal diseases. Recent studies have reported that gastric microbiota might be modified by the colonization, favoring gastric lesions' development. In Chile, the region of La Araucanía concentrates a high risk of gastric cancer associated with colonization, rurality, poverty, and Mapuche ethnicity.

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colonizes half of the human population. Age, ethnicity, and socioeconomic status are factors that influence the prevalence of the infection. This is important in southern Chile, one of the most unequal regions in the world, where a significant difference in the health access of the population occurs due to the existence of two competing health systems.

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Non-alcoholic fatty liver disease (NAFDL) includes fatty liver or simple steatosis, characterized by lipid deposits in hepatocytes and more advanced stages such as steatohepatitis (NASH) and non-alcoholic cirrhosis. Physical inactivity, hypercaloric and unbalanced diet together with aging play a key role in the pathogenesis of NAFLD and are strongly associated with metabolic and physical activity continue to be major components in prevention and first-line treatment to attenuate or reverse NAFLD. Dietary patterns, their composition and weight reduction would be the most relevant nutritional aspects in NAFDL treatment.

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Article Synopsis
  • Human fascioliasis, a rare zoonotic infection in Chile, has two main clinical phases: the acute phase features symptoms like right side abdominal pain, fever, and liver enlargement, lasting between 2 weeks to 4 months.
  • A case study highlights a 57-year-old woman who showed no typical risk factors or symptoms of fascioliasis but had a liver lesion diagnosed as intrahepatic cholangiocarcinoma through advanced imaging techniques.
  • Upon surgical removal of the liver section, pathology revealed the presence of trematode eggs indicating fascioliasis, showcasing a potentially misdiagnosed case of a rare disease linked to Fasciola hepatica.
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